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Carbohydrates are one of the four main building blocks of life, and are categorized as monosaccharides (sugars), oligosaccharides and polysaccharides. Each sugar can exist in two alternative anomers (in which

Carbohydrates are one of the four main building blocks of life, and are categorized as monosaccharides (sugars), oligosaccharides and polysaccharides. Each sugar can exist in two alternative anomers (in which a hydroxy group at C-1 takes different orientations) and each pair of sugars can form different epimers (isomers around the stereocentres connecting the sugars). This leads to a vast combinatorial complexity, intractable to mass spectrometry and requiring large amounts of sample for NMR characterization.

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    Date Created
    • 2016-12-21
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    • Digital object identifier: 10.1038/ncomms13868
    • Identifier Type
      International standard serial number
      Identifier Value
      2041-1723
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    Im, J., Biswas, S., Liu, H., Zhao, Y., Sen, S., Biswas, S., . . . Zhang, P. (2016). Electronic single-molecule identification of carbohydrate isomers by recognition tunnelling. Nature Communications, 7, 13868. doi:10.1038/ncomms13868

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