Description

Alzheimer’s disease (AD) affects over 5 million individuals each year in the United States. Furthermore, most cases of AD are sporadic, making it extremely difficult to model and study in

Alzheimer’s disease (AD) affects over 5 million individuals each year in the United States. Furthermore, most cases of AD are sporadic, making it extremely difficult to model and study in vitro. CRISPR/Cas9 and base editing technologies have been of recent interest because of their ability to create single nucleotide edits at nearly any genomic sequence using a Cas9 protein and a guide RNA (sgRNA). Currently, there is no available phenotype to differentiate edited cells from unedited cells.

4.36 MB application/pdf

Download restricted until 2022-05-01.

Download count: 0

Details

Contributors
Date Created
  • 2020
Resource Type
  • Text
  • Collections this item is in
    Note
    • Masters Thesis Biomedical Engineering 2020

    Machine-readable links