Description

Recombinases are powerful tools for genome engineering and synthetic biology, however recombinases are limited by a lack of user-programmability and often require complex directed-evolution experiments to retarget specificity. Conversely, CRISPR systems have extreme versatility yet can induce off-target mutations and karyotypic destabilization.

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    Date Created
    2018
    Resource Type
  • Text
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    Note
    • Partial requirement for: M.S., Arizona State University, 2018
      Note type
      thesis
    • Includes bibliographical references (pages 16-18)
      Note type
      bibliography
    • Field of study: Biology

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    by Kylie S Standage-Beier

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