Description
Serial femtosecond crystallography (SFX) has opened a new era in crystallography by permitting nearly damage-free, room-temperature structure determination of challenging proteins such as membrane proteins. In SFX, femtosecond X-ray free-electron laser pulses produce diffraction snapshots from nanocrystals and microcrystals delivered in a liquid jet, which leads to high protein consumption.
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Contributors
- Conrad, Chelsie (Author)
- Basu, Shibom (Author)
- James, Daniel (Author)
- Wang, Dingjie (Author)
- Schaffer, Alexander (Author)
- Roy Chowdhury, Shatabdi (Author)
- Zatsepin, Nadia (Author)
- Aquila, Andrew (Author)
- Coe, Jesse (Author)
- Gati, Cornelius (Author)
- Hunter, Mark S. (Author)
- Koglin, Jason E. (Author)
- Kupitz, Christopher (Author)
- Nelson, Garrett (Author)
- Subramanian, Ganesh (Author)
- White, Thomas A. (Author)
- Zhao, Yun (Author)
- Zook, James (Author)
- Boutet, Sebastien (Author)
- Cherezov, Vadim (Author)
- Spence, John (Author)
- Fromme, Raimund (Author)
- Weierstall, Uwe (Author)
- Fromme, Petra (Author)
- Department of Chemistry and Biochemistry (Contributor)
- Biodesign Institute (Contributor)
- Applied Structural Discovery (Contributor)
- College of Liberal Arts and Sciences (Contributor)
- Department of Physics (Contributor)
- School of Molecular Sciences (Contributor)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2015-06-30
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Identifier
- Digital object identifier: 10.1107/S2052252515009811
- Identifier Value2052-2525
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- View the article as published at http://journals.iucr.org/m/issues/2015/04/00/mf5010/index.html, opens in a new window
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Conrad, C. E., Basu, S., James, D., Wang, D., Schaffer, A., Roy-Chowdhury, S., . . . Fromme, P. (2015). A novel inert crystal delivery medium for serial femtosecond crystallography. IUCrJ, 2(4), 421-430. doi:10.1107/s2052252515009811