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pH and fermentable substrates impose selective pressures on gut microbial communities and their metabolisms. We evaluated the relative contributions of pH, alkalinity, and substrate on microbial community structure, metabolism, and

pH and fermentable substrates impose selective pressures on gut microbial communities and their metabolisms. We evaluated the relative contributions of pH, alkalinity, and substrate on microbial community structure, metabolism, and functional interactions using triplicate batch cultures started from fecal slurry and incubated with an initial pH of 6.0, 6.5, or 6.9 and 10 mM glucose, fructose, or cellobiose as the carbon substrate. We analyzed 16S rRNA gene sequences and fermentation products. Microbial diversity was driven by both pH and substrate type.

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    Date Created
    • 2017-05-03
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1128/mSphere.00047-17
    • Identifier Type
      International standard serial number
      Identifier Value
      2379-5042
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    Ilhan, Z. E., Marcus, A. K., Kang, D., Rittmann, B. E., & Krajmalnik-Brown, R. (2017). PH-Mediated Microbial and Metabolic Interactions in Fecal Enrichment Cultures. MSphere, 2(3). doi:10.1128/msphere.00047-17

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