Description

There is a critical need for more accurate, highly sensitive and specific assay for disease diagnosis and management. A novel, multiplexed, single sensor using rapid and label free electrochemical impedance

There is a critical need for more accurate, highly sensitive and specific assay for disease diagnosis and management. A novel, multiplexed, single sensor using rapid and label free electrochemical impedance spectroscopy tuning method has been developed. The key challenges while monitoring multiple targets is frequency overlap. Here we describe the methods to circumvent the overlap, tune by use of nanopartide (NP) and discuss the various fabrication and characterization methods to develop this technique.

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Date Created
  • 2013-09-09
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  • Text
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    Identifier
    • Digital object identifier: 10.1016/j.ymeth.2013.04.015
    • Identifier Type
      International standard serial number
      Identifier Value
      1046-2023
    Note
    • NOTICE: this is the author’s version of a work that was accepted for publication in Methods. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Methods, 61(1), 39-51. http://dx.doi.org/10.1016/j.ymeth.2013.04.015, opens in a new window

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    This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.

    La Belle, J. T., Fairchild, A., Demirok, U. K., & Verma, A. (2013). Method for fabrication and verification of conjugated nanoparticle-antibody tuning elements for multiplexed electrochemical biosensors. Methods, 61(1), 39-51. doi:10.1016/j.ymeth.2013.04.015

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