The apolipoprotein E (APOE) e4 genotype is the most prevalent known genetic risk factor for Alzheimer's disease (AD). In this paper, we examined the longitudinal effect of APOE e4 on hippocampal morphometry in Alzheimer's Disease Neuroimaging Initiative (ADNI). Generally, atrophy of hippocampus has more chance occurs in AD patients who carrying the APOE e4 allele than those who are APOE e4 noncarriers.
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- Partial requirement for: M.C.St., Arizona State University, 2015Note typethesis
- Includes bibliographical references (p. 38-49)Note typebibliography
- Field of study: Computer science