Description
Cyanovirin-N (CV-N) is a naturally occurring lectin originally isolated from the cyanobacteria Nostoc ellipsosporum. This 11 kDa lectin is 101 amino acids long with two binding sites, one at each end of the protein. CV-N specifically binds to terminal Manα1-2Manα motifs on the branched, high mannose Man9 and Man8 glycosylations found on enveloped viruses including Ebola, Influenza, and HIV.
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Contributors
- Ruben, Melissa (Author)
- Ghirlanda, Giovanna (Thesis advisor)
- Allen, James (Committee member)
- Wachter, Rebekka (Committee member)
- Arizona State University (Publisher)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2013
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Note
- Partial requirement for: Ph.D., Arizona State University, 2013Note typethesis
- Includes bibliographical referencesNote typebibliography
- Field of study: Biochemistry
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Statement of Responsibility
by Melissa Ruben