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Cancer is sometimes depicted as a reversion to single cell behavior in cells adapted to live in a multicellular assembly. If this is the case, one would expect that mutation

Cancer is sometimes depicted as a reversion to single cell behavior in cells adapted to live in a multicellular assembly. If this is the case, one would expect that mutation in cancer disrupts functional mechanisms that suppress cell-level traits detrimental to multicellularity. Such mechanisms should have evolved with or after the emergence of multicellularity.

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    Date Created
    • 2017-04-25
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0176258
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    Cisneros, L., Bussey, K. J., Orr, A. J., Miočević, M., Lineweaver, C. H., & Davies, P. (2017). Ancient genes establish stress-induced mutation as a hallmark of cancer. Plos One, 12(4). doi:10.1371/journal.pone.0176258

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