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In the decade since Yamanaka and colleagues described methods to reprogram somatic cells into a pluripotent state, human induced pluripotent stem cells (hiPSCs) have demonstrated tremendous promise in numerous disease

In the decade since Yamanaka and colleagues described methods to reprogram somatic cells into a pluripotent state, human induced pluripotent stem cells (hiPSCs) have demonstrated tremendous promise in numerous disease modeling, drug discovery, and regenerative medicine applications. More recently, the development and refinement of advanced gene transduction and editing technologies have further accelerated the potential of hiPSCs. In this review, we discuss the various gene editing technologies that are being implemented with hiPSCs.

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    Date Created
    • 2017-02-06
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  • Text
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    Identifier
    • Digital object identifier: 10.3390/cells6010005
    • Identifier Type
      International standard serial number
      Identifier Value
      2073-4409

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    Brookhouser, N., Raman, S., Potts, C., & Brafman, D. A. (2017). May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells. Cells, 6(1), 5. doi:10.3390/cells6010005

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