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Accumulating data from genome-wide association studies (GWAS) have provided a collection of novel candidate genes associated with complex diseases, such as atherosclerosis. We identified an atherosclerosis-associated single-nucleotide polymorphism (SNP) located

Accumulating data from genome-wide association studies (GWAS) have provided a collection of novel candidate genes associated with complex diseases, such as atherosclerosis. We identified an atherosclerosis-associated single-nucleotide polymorphism (SNP) located in the intron of the long noncoding RNA (lncRNA) LINC00305 by searching the GWAS database. Although the function of LINC00305 is unknown, we found that LINC00305 expression is enriched in atherosclerotic plaques and monocytes.

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    Date Created
    • 2017-04-10
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    • Digital object identifier: 10.1038/srep46204
    • Identifier Type
      International standard serial number
      Identifier Value
      2045-2322
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    Zhang, D., Wang, W., Xiong, J., Xie, X., Cui, S., Zhao, Z., . . . Liu, D. (2017). Long noncoding RNA LINC00305 promotes inflammation by activating the AHRR-NF-κB pathway in human monocytes. Scientific Reports, 7, 46204. doi:10.1038/srep46204

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