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The field of tissue engineering entered a new era with the development of human pluripotent stem cells (hPSCs), which are capable of unlimited expansion whilst retaining the potential to differentiate

The field of tissue engineering entered a new era with the development of human pluripotent stem cells (hPSCs), which are capable of unlimited expansion whilst retaining the potential to differentiate into all mature cell populations. However, these cells harbor significant risks, including tumor formation upon transplantation. One way to mitigate this risk is to develop expandable progenitor cell populations with restricted differentiation potential.

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    Date Created
    • 2015-11-10
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  • Text
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    Identifier
    • Digital object identifier: 10.7554/eLife.08413
    • Identifier Type
      International standard serial number
      Identifier Value
      2050-084X

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    Kumar, N., Richter, J., Cutts, J., Bush, K. T., Trujillo, C., Nigam, S. K., . . . Willert, K. (2015). Generation of an expandable intermediate mesoderm restricted progenitor cell line from human pluripotent stem cells. ELife, 4. doi:10.7554/elife.08413

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