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Although the majority of late-onset Alzheimer's disease (AD) patients are labeled sporadic, multiple genetic risk variants have been identified, the most powerful and prevalent of which is the e4 variant

Although the majority of late-onset Alzheimer's disease (AD) patients are labeled sporadic, multiple genetic risk variants have been identified, the most powerful and prevalent of which is the e4 variant of the Apolipoprotein E (APOE) gene. Here, we generated human induced pluripotent stem cell (hiPSC) lines from the peripheral blood mononuclear cells (PBMCs) of a clinically diagnosed AD patient [ASUi003-A] and a non-demented control (NDC) patient [ASUi004-A] homozygous for the APOE4 risk allele.

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    Date Created
    • 2017-07-10
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1016/j.scr.2017.07.003
    • Identifier Type
      International standard serial number
      Identifier Value
      1873-5061
    • Identifier Type
      International standard serial number
      Identifier Value
      1876-7753

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    Brookhouser, N., Zhang, P., Caselli, R., Kim, J. J., & Brafman, D. A. (2017). Generation and characterization of human induced pluripotent stem cell (hiPSC) lines from an Alzheimers disease (ASUi003-A) and non-demented control (ASUi004-A) patient homozygous for the Apolipoprotein e4 (APOE4) risk variant. Stem Cell Research, 25, 266-269. doi:10.1016/j.scr.2017.07.003

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