Description

Extracellular Vesicles (EVs), particularly exosomes, are of considerable interest as tumor biomarkers since tumor-derived EVs contain a broad array of information about tumor pathophysiology including its metabolic and metastatic status.

Extracellular Vesicles (EVs), particularly exosomes, are of considerable interest as tumor biomarkers since tumor-derived EVs contain a broad array of information about tumor pathophysiology including its metabolic and metastatic status. However, current EV based assays cannot distinguish between EV biomarker changes by altered secretion of EVs during diseased conditions like cancer, inflammation, etc. that express a constant level of a given biomarker, stable secretion of EVs with altered biomarker expression, or a combination of these two factors.

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Date Created
  • 2019
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  • Text
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    Note
    • Partial requirement for: Ph.D., Arizona State University, 2019
      Note type
      thesis
    • Includes bibliographical references (pages 92-108)
      Note type
      bibliography
    • Field of study: Biomedical Engineering

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    by Meryl Rodrigues

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