Data-driven applications are becoming increasingly complex with support for processing events and data streams in a loosely-coupled distributed environment, providing integrated access to heterogeneous data sources such as relational databases and XML documents. This dissertation explores the use of materialized views over structured heterogeneous data sources to support multiple query optimization in a distributed event stream processing framework that supports such applications involving various query expressions for detecting events, monitoring conditions, handling data streams, and querying data. Materialized views store the results of the computed view so that subsequent access to the view retrieves the materialized results, avoiding the cost of recomputing the entire view from base data sources. Using a service-based metadata repository that provides metadata level access to the various language components in the system, a heuristics-based algorithm detects the common subexpressions from the queries represented in a mixed multigraph model over relational and structured XML data sources. These common subexpressions can be relational, XML or a hybrid join over the heterogeneous data sources. This research examines the challenges in the definition and materialization of views when the heterogeneous data sources are retained in their native format, instead of converting the data to a common model. LINQ serves as the materialized view definition language for creating the view definitions. An algorithm is introduced that uses LINQ to create a data structure for the persistence of these hybrid views. Any changes to base data sources used to materialize views are captured and mapped to a delta structure. The deltas are then streamed within the framework for use in the incremental update of the materialized view. Algorithms are presented that use the magic sets query optimization approach to both efficiently materialize the views and to propagate the relevant changes to the views for incremental maintenance. Using representative scenarios over structured heterogeneous data sources, an evaluation of the framework demonstrates an improvement in performance. Thus, defining the LINQ-based materialized views over heterogeneous structured data sources using the detected common subexpressions and incrementally maintaining the views by using magic sets enhances the efficiency of the distributed event stream processing environment.