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Many natural and synthetic quinones have shown biological and pharmacological activity. Some of them have also shown anticancer activity. Ubiquinone (CoQ10) which is a natural quinone, is a component of

Many natural and synthetic quinones have shown biological and pharmacological activity. Some of them have also shown anticancer activity. Ubiquinone (CoQ10) which is a natural quinone, is a component of the electron transport chain and participates in generation of ATP (adenosine triphosphate). Cellular oxidative stress is key feature of many neurodegenerative diseases such as Friedreich's ataxia, Alzheimer's disease and Parkinson's disease. The increased generation of reactive oxygen species damages cell membranes and leads to cell death.

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    Date Created
    • 2011
    Resource Type
  • Text
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    Note
    • Partial requirement for: M.S., Arizona State University, 2011
      Note type
      thesis
    • Includes bibliographical references (p. 56-61)
      Note type
      bibliography
    • Field of study: Biochemistry

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    by Nidhi Raghav

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