Five immunocompetent C57BL/6-cBrd/cBrd/Cr (albino C57BL/6) mice were injected with GL261-luc2 cells, a cell line sharing characteristics of human glioblastoma multiforme (GBM). The mice were imaged using magnetic resonance (MR) at five separate time points to characterize growth and development of the tumor. After 25 days, the final tumor volumes of the mice varied from 12 mm[superscript 3] to 62 mm[superscript 3], even though mice were inoculated from the same tumor cell line under carefully controlled conditions.
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- Rutter, Erica (Contributor)
- Stepien, Tracy (Contributor)
- Anderies, Barrett (Contributor)
- Plasencia, Jonathan (Contributor)
- Woolf, Eric C. (Author)
- Scheck, Adrienne C. (Author)
- Turner, Gregory H. (Author)
- Liu, Qingwei (Author)
- Frakes, David (Contributor)
- Kodibagkar, Vikram (Contributor)
- Kuang, Yang (Contributor)
- Preul, Mark C. (Author)
- Kostelich, Eric (Contributor)
- College of Liberal Arts and Sciences (Contributor)
- 2017-05-31
- Digital object identifier: 10.1038/s41598-017-02462-0
- Identifier TypeInternational standard serial numberIdentifier Value2045-2322
- The final version of this article, as published in Scientific Reports, can be viewed online at: http://www.nature.com/articles/s41598-017-02462-0, opens in a new window
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Rutter, E. M., Stepien, T. L., Anderies, B. J., Plasencia, J. D., Woolf, E. C., Scheck, A. C., . . . Kostelich, E. J. (2017). Mathematical Analysis of Glioma Growth in a Murine Model. Scientific Reports, 7(1). doi:10.1038/s41598-017-02462-0