Description

The broad recognition specificity exhibited by integrin α[subscript M]β[subscript 2] (Mac-1, CD11b/CD18) has allowed this adhesion receptor to play innumerable roles in leukocyte biology, yet we know little about how

The broad recognition specificity exhibited by integrin α[subscript M]β[subscript 2] (Mac-1, CD11b/CD18) has allowed this adhesion receptor to play innumerable roles in leukocyte biology, yet we know little about how and why α[subscript M]β[subscript 2] binds its multiple ligands. Within α[subscript M]β[subscript 2], the α[subscript M]I-domain is responsible for integrin’s multiligand binding properties.

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Date Created
  • 2015-02-17
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  • Text
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    Identifier
    • Digital object identifier: 10.1021/bi5013782
    • Identifier Type
      International standard serial number
      Identifier Value
      0006-2960
    • Identifier Type
      International standard serial number
      Identifier Value
      1520-4995
    Note
    • This document is the Accepted Manuscript version of a Published Work that appeared in final form in BIOCHEMISTRY, copyright American Chemical Society, after peer review and technical editing by the publisher. To access the final published work, see http://dx.doi.org/10.1021/bi5013782, opens in a new window

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    This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.

    Podolnikova, Nataly P., Podolnikov, Andriy V., Haas, Thomas A., Lishko, Valeryi K., & Ugarova, Tatiana P. (2015). Ligand Recognition Specificity of Leukocyte Integrin alpha(M)beta(2) (Mac-1, CD11b/CD18) and Its Functional Consequences. BIOCHEMISTRY, 54(6), 1408-1420. http://dx.doi.org/10.1021/bi5013782

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