Description

Background
Rats fed high fat (HFD) or high sucrose (HSD) diets develop increased adiposity as well as impaired vasodilatory responsiveness stemming from oxidative stress. Moreover, HFD rats become hypertensive compared

Background
Rats fed high fat (HFD) or high sucrose (HSD) diets develop increased adiposity as well as impaired vasodilatory responsiveness stemming from oxidative stress. Moreover, HFD rats become hypertensive compared to either control (Chow) or HSD fed rats, suggesting elevated vascular tone. We hypothesized that rats with increased adiposity and oxidative stress demonstrate augmented pressure-induced vasoconstriction (i.e. myogenic tone) that could account for the hypertensive state.
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    Date Created
    • 2012-03-16
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    Identifier
    • Digital object identifier: 10.1186/1743-7075-9-18
    • Identifier Type
      International standard serial number
      Identifier Value
      1743-7075
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    Sweazea, K. L., & Walker, B. R. (2012). Impaired myogenic tone in mesenteric arteries from overweight rats. Nutrition & Metabolism, 9(1), 18. doi:10.1186/1743-7075-9-18

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