Background
Malignant brain tumors affect people of all ages and are the second leading cause of cancer deaths in children. While current treatments are effective and improve survival, there remains a substantial need for more efficacious therapeutic modalities. The ketogenic diet (KD) - a high-fat, low-carbohydrate treatment for medically refractory epilepsy - has been suggested as an alternative strategy to inhibit tumor growth by altering intrinsic metabolism, especially by inducing glycopenia.
Methods
Download count: 0
Details
- Stafford, Phillip (Contributor)
- Abdelwahab, Mohammed G. (Author)
- Kim, Do Young (Author)
- Preul, Mark C. (Author)
- Rho, Jong M. (Author)
- Scheck, Adrienne C. (Author)
- Biodesign Institute (Contributor)
- 2010-09-10
- Digital object identifier: 10.1186/1743-7075-7-74
- Identifier TypeInternational standard serial numberIdentifier Value1743-7075
- The electronic version of this article is the complete one and can be found online at: http://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-7-74, opens in a new window
Citation and reuse
Cite this item
This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.
Stafford, P., Abdelwahab, M. G., Kim, D., Preul, M. C., Rho, J. M., & Scheck, A. C. (2010). The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma. Nutrition & Metabolism, 7(1), 74. doi:10.1186/1743-7075-7-74