Description

RseA sequesters RpoE (σ[superscript E]) to the inner membrane of Escherichia coli when envelope stress is low. Elevated envelope stress triggers RseA cleavage by the sequential action of two membrane

RseA sequesters RpoE (σ[superscript E]) to the inner membrane of Escherichia coli when envelope stress is low. Elevated envelope stress triggers RseA cleavage by the sequential action of two membrane proteases, DegS and RseP, releasing σ[superscript E] to activate an envelope stress reducing pathway. Revertants of a ΔdegP ΔbamB strain, which fails to grow at 37°C due to high envelope stress, harbored mutations in the rseA and rpoE genes.

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    Date Created
    • 2012-03-16
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0033979
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    Leiser, O. P., Charlson, E. S., Gerken, H., & Misra, R. (2012). Reversal of the ΔdegP Phenotypes by a Novel rpoE Allele of Escherichia coli. PLoS ONE, 7(3). doi:10.1371/journal.pone.0033979

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