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A distinct pathovar of Salmonella enterica serovar Typhimurium, ST313, has emerged in sub-Saharan Africa as a major cause of fatal bacteremia in young children and HIV-infected adults. D23580, a multidrug

A distinct pathovar of Salmonella enterica serovar Typhimurium, ST313, has emerged in sub-Saharan Africa as a major cause of fatal bacteremia in young children and HIV-infected adults. D23580, a multidrug resistant clinical isolate of ST313, was previously shown to have undergone genome reduction in a manner that resembles that of the more human-restricted pathogen, Salmonella enterica serovar Typhi. It has since been shown through tissue distribution studies that D23580 is able to establish an invasive infection in chickens.

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Date Created
  • 2015-06-19
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  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pntd.0003839
    • Identifier Type
      International standard serial number
      Identifier Value
      1935-2727
    • Identifier Type
      International standard serial number
      Identifier Value
      1935-2735

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    Yang, J., Barrila, J., Roland, K. L., Kilbourne, J., Ott, C. M., Forsyth, R. J., & Nickerson, C. A. (2015). Characterization of the Invasive, Multidrug Resistant Non-typhoidal Salmonella Strain D23580 in a Murine Model of Infection. PLOS Neglected Tropical Diseases, 9(6). doi:10.1371/journal.pntd.0003839

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