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Chronic manganese (Mn) exposure is associated with neuromotor and neurocognitive deficits, but the exact mechanism of Mn neurotoxicity is still unclear. With the advent of magnetic resonance imaging (MRI), in-vivo

Chronic manganese (Mn) exposure is associated with neuromotor and neurocognitive deficits, but the exact mechanism of Mn neurotoxicity is still unclear. With the advent of magnetic resonance imaging (MRI), in-vivo analysis of brain structures has become possible. Among different sub-cortical structures, the basal ganglia (BG) has been investigated as a putative anatomical biomarker in MR-based studies of Mn toxicity. However, previous investigations have yielded inconsistent results in terms of regional MR signal intensity changes.

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    Date Created
    • 2017-02-03
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  • Text
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    • Digital object identifier: 10.1038/srep41804
    • Identifier Type
      International standard serial number
      Identifier Value
      2045-2322
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    Lao, Y., Dion, L., Gilbert, G., Bouchard, M. F., Rocha, G., Wang, Y., . . . Saint-Amour, D. (2017). Mapping the basal ganglia alterations in children chronically exposed to manganese. Scientific Reports, 7, 41804. doi:10.1038/srep41804

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