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The process of cell fate determination has been depicted intuitively as cells travelling and resting on a rugged landscape, which has been probed by various theoretical studies. However, few studies

The process of cell fate determination has been depicted intuitively as cells travelling and resting on a rugged landscape, which has been probed by various theoretical studies. However, few studies have experimentally demonstrated how underlying gene regulatory networks shape the landscape and hence orchestrate cellular decision-making in the presence of both signal and noise.

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    Date Created
    • 2017-04-11
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  • Text
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    Identifier
    • Digital object identifier: 10.7554/eLife.23702
    • Identifier Type
      International standard serial number
      Identifier Value
      2050-084X

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    Wu, F., Su, R., Lai, Y., & Wang, X. (2017). Engineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination. ELife, 6. doi:10.7554/elife.23702

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