Risk factors for breast cancer are often confusing and contradictory. Discrepancies are likely due to different subtypes having divergent risk factors. An important distinction between breast cancer subtypes is hormone-receptor status. Compared to women diagnosed with estrogen receptor positive (ER+) breast cancer, those with estrogen receptor negative (ER−) tumors are usually diagnosed at a younger age and have a higher mortality . Few studies have attempted to explain ‘why’ breast cancer subtypes have different risk factors.
Hidaka, B. H., & Boddy, A. M. (2016). Is estrogen receptor negative breast cancer risk associated with a fast life history strategy? Evolution, Medicine, and Public Health, 2016(1), 17-20. doi:10.1093/emph/eov034
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