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Synthetic genetics is a subdiscipline of synthetic biology that aims to develop artificial genetic polymers (also referred to as xeno-nucleic acids or XNAs) that can replicate in vitro and eventually

Synthetic genetics is a subdiscipline of synthetic biology that aims to develop artificial genetic polymers (also referred to as xeno-nucleic acids or XNAs) that can replicate in vitro and eventually in model cellular organisms. This field of science combines organic chemistry with polymerase engineering to create alternative forms of DNA that can store genetic information and evolve in response to external stimuli. Practitioners of synthetic genetics postulate that XNA could be used to safeguard synthetic biology organisms by storing genetic information in orthogonal chromosomes.

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    Date Created
    • 2015-12-15
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    Identifier
    • Digital object identifier: 10.1093/nar/gkv1472
    • Identifier Type
      International standard serial number
      Identifier Value
      1362-4962
    • Identifier Type
      International standard serial number
      Identifier Value
      0305-1048
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    Anosova, I., Kowal, E. A., Dunn, M. R., Chaput, J. C., Van Horn, W. D., & Egli, M. (2015). The structural diversity of artificial genetic polymers. Nucleic Acids Research, 44(3), 1007-1021. doi:10.1093/nar/gkv1472

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