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The worst Ebola virus (EV) outbreak in history has hit Liberia, Sierra Leone and Guinea hardest and the trend lines in this crisis are grave, and now represents a global

The worst Ebola virus (EV) outbreak in history has hit Liberia, Sierra Leone and Guinea hardest and the trend lines in this crisis are grave, and now represents a global public health threat concern. Limited therapeutic and/or prophylactic options are available for people suffering from Ebola virus disease (EVD) and further complicate the situation. Previous studies suggested that the EV glycoprotein (GP) is the main determinant causing structural damage of endothelial cells that triggers the hemorrhagic diathesis, but molecular mechanisms underlying this phenomenon remains elusive.

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    Date Created
    • 2015-02-19
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.3389/fmicb.2015.00135
    • Identifier Type
      International standard serial number
      Identifier Value
      1664-1078

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    Veljkovic, V., Glisic, S., Muller, C. P., Scotch, M., Branch, D. R., Perovic, V. R., . . . Colombatti, A. (2015). In silico analysis suggests interaction between Ebola virus and the extracellular matrix. Frontiers in Microbiology, 6. doi:10.3389/fmicb.2015.00135

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