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Objective: Survival time is an important type of outcome variable in treatment research. Currently, limited guidance is available regarding performing mediation analyses with survival outcomes, which generally do not have

Objective: Survival time is an important type of outcome variable in treatment research. Currently, limited guidance is available regarding performing mediation analyses with survival outcomes, which generally do not have normally distributed errors, and contain unobserved (censored) events. We present considerations for choosing an approach, using a comparison of semi-parametric proportional hazards (PH) and fully parametric accelerated failure time (AFT) approaches for illustration.

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    Date Created
    • 2016-03-30
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.3389/fpsyg.2016.00423
    • Identifier Type
      International standard serial number
      Identifier Value
      1664-1078

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    Gelfand, L. A., Mackinnon, D. P., Derubeis, R. J., & Baraldi, A. N. (2016). Mediation Analysis with Survival Outcomes: Accelerated Failure Time vs. Proportional Hazards Models. Frontiers in Psychology, 7. doi:10.3389/fpsyg.2016.00423

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