Description
We described the rapid production of the domain III (DIII) of the envelope (E) protein in plants as a vaccine candidate for West Nile Virus (WNV). Using various combinations of vector modules of a deconstructed viral vector expression system, DIII was produced in three subcellular compartments in leaves of Nicotiana benthamiana by transient expression.
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Contributors
- He, Junyun (Author)
- Peng, Li (Author)
- Lai, Huafang (Author)
- Hurtado, Jonathan (Author)
- Stahnke, Jake (Author)
- Chen, Qiang (Author)
- ASU Biodesign Center Immunotherapy, Vaccines and Virotherapy (Contributor)
- Biodesign Institute (Contributor)
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2014-04-03
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Identifier
- Digital object identifier: 10.1155/2014/952865
- Identifier TypeInternational standard serial numberIdentifier Value2314-6133
- Identifier TypeInternational standard serial numberIdentifier Value2314-6141
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- View the article as published at https://www.hindawi.com/journals/bmri/2014/952865/, opens in a new window
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He, J., Peng, L., Lai, H., Hurtado, J., Stahnke, J., & Chen, Q. (2014). A Plant-Produced Antigen Elicits Potent Immune Responses against West Nile Virus in Mice. BioMed Research International, 2014, 1-10. doi:10.1155/2014/952865