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Understanding the extent to which vascular disease and its risk factors are associated with prodromal dementia, notably Alzheimer's disease (AD), may enhance predictive accuracy as well as guide early interventions.

Understanding the extent to which vascular disease and its risk factors are associated with prodromal dementia, notably Alzheimer's disease (AD), may enhance predictive accuracy as well as guide early interventions. One promising avenue to determine this relationship consists of looking for reliable and sensitive in-vivo imaging methods capable of characterizing the subtle brain alterations before the clinical manifestations. However, little is known from the imaging perspective about how risk factors such as vascular disease influence AD progression.

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    Date Created
    • 2016-12-28
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    Identifier
    • Digital object identifier: 10.1016/j.nicl.2016.12.027
    • Identifier Type
      International standard serial number
      Identifier Value
      2213-1582
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    Lao, Y., Nguyen, B., Tsao, S., Gajawelli, N., Law, M., Chui, H., . . . Leporé, N. (2017). A T1 and DTI fused 3D corpus callosum analysis in MCI subjects with high and low cardiovascular risk profile. NeuroImage: Clinical, 14, 298-307. doi:10.1016/j.nicl.2016.12.027

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