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Several Zika virus (ZIKV) vaccine candidates have recently been described which use inactivated whole virus, DNA or RNA that express the virus’ Envelope (E) glycoprotein as the antigen. These were

Several Zika virus (ZIKV) vaccine candidates have recently been described which use inactivated whole virus, DNA or RNA that express the virus’ Envelope (E) glycoprotein as the antigen. These were successful in stimulating production of virus-targeted antibodies that protected animals against ZIKV challenges, but their use potentially will predispose vaccinated individuals to infection by the related Dengue virus (DENV).

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    Date Created
    • 2017-08-09
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1038/s41598-017-08247-9
    • Identifier Type
      International standard serial number
      Identifier Value
      2045-2322
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    Yang, M., Lai, H., Sun, H., & Chen, Q. (2017). Virus-like particles that display Zika virus envelope protein domain III induce potent neutralizing immune responses in mice. Scientific Reports, 7(1). doi:10.1038/s41598-017-08247-9

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