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MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression and are implicated in the etiology of several neuropsychiatric disorders, including substance use disorders (SUDs). Using in silico genome-wide sequence analyses,

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression and are implicated in the etiology of several neuropsychiatric disorders, including substance use disorders (SUDs). Using in silico genome-wide sequence analyses, we identified miR-495 as a miRNA whose predicted targets are significantly enriched in the Knowledgebase for Addiction Related Genes (ARG) database (KARG; http://karg.cbi.pku.edu.cn).

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    Date Created
    • 2017-01-13
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    Identifier
    • Digital object identifier: 10.1038/mp.2016.238
    • Identifier Type
      International standard serial number
      Identifier Value
      1359-4184
    • Identifier Type
      International standard serial number
      Identifier Value
      1476-5578
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    Bastle, R. M., Oliver, R. J., Gardiner, A. S., Pentkowski, N. S., Bolognani, F., Allan, A. M., . . . Perrone-Bizzozero, N. I. (2017). In silico identification and in vivo validation of miR-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens. Molecular Psychiatry. doi:10.1038/mp.2016.238

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