Matching Items (410)
Description
This research investigated using impedance as a minimally invasive oral cancer-screening tool by modeling healthy and diseased tissue. This research developed an ultra-structurally based tissue model for oral mucosa that is versatile enough to be easily modified to mimic the passive electrical impedance responses of multiple benign and cancerous tissue types. This new model provides answers to biologically meaningful questions related to the impedance response of healthy and diseased tissues. This model breaks away from the old empirical top down "black box" Thèvinin equivalent model. The new tissue model developed here was created from a bottom up perspective resulting in a model that is analogous to having a "Transparent Box" where each network element relating to a specific structural component is known. This new model was developed starting with sub cellular ultra-structural components such as membranes, proteins and electrolytes. These components formed the basic network elements and topology of the organelles. The organelle networks combine to form the cell networks. The cell networks combine to make networks of cell layers and the cell layers were combined into tissue networks. This produced the complete "Transparent Box" model for normal tissue. This normal tissue model was modified for disease based on the ultra-structural pathology of each disease. The diseased tissues evaluated include cancers type one through type three; necrotic-inflammation, hyperkeratosis and the compound condition of hyperkeratosis over cancer type two. The impedance responses for each of the disease were compared side by side with the response of normal healthy tissue. Comparative evidence from the models showed the structural changes in cancer produce a unique identifiable impedance "finger print." The evaluation of the "Transparent Box" model for normal tissues and diseased tissues show clear support for using comparative impedance measurements as a clinical tool for oral cancer screening.
ContributorsPelletier, Peter Robert (Author) / Kozicki, Michael (Thesis advisor) / Towe, Bruce (Committee member) / Saraniti, Marco (Committee member) / Goryll, Michael (Committee member) / Arizona State University (Publisher)
Created2012
Description
Super-Resolution (SR) techniques are widely developed to increase image resolution by fusing several Low-Resolution (LR) images of the same scene to overcome sensor hardware limitations and reduce media impairments in a cost-effective manner. When choosing a solution for the SR problem, there is always a trade-off between computational efficiency and High-Resolution (HR) image quality. Existing SR approaches suffer from extremely high computational requirements due to the high number of unknowns to be estimated in the solution of the SR inverse problem. This thesis proposes efficient iterative SR techniques based on Visual Attention (VA) and perceptual modeling of the human visual system. In the first part of this thesis, an efficient ATtentive-SELective Perceptual-based (AT-SELP) SR framework is presented, where only a subset of perceptually significant active pixels is selected for processing by the SR algorithm based on a local contrast sensitivity threshold model and a proposed low complexity saliency detector. The proposed saliency detector utilizes a probability of detection rule inspired by concepts of luminance masking and visual attention. The second part of this thesis further enhances on the efficiency of selective SR approaches by presenting an ATtentive (AT) SR framework that is completely driven by VA region detectors. Additionally, different VA techniques that combine several low-level features, such as center-surround differences in intensity and orientation, patch luminance and contrast, bandpass outputs of patch luminance and contrast, and difference of Gaussians of luminance intensity are integrated and analyzed to illustrate the effectiveness of the proposed selective SR frameworks. The proposed AT-SELP SR and AT-SR frameworks proved to be flexible by integrating a Maximum A Posteriori (MAP)-based SR algorithm as well as a fast two-stage Fusion-Restoration (FR) SR estimator. By adopting the proposed selective SR frameworks, simulation results show significant reduction on average in computational complexity with comparable visual quality in terms of quantitative metrics such as PSNR, SNR or MAE gains, and subjective assessment. The third part of this thesis proposes a Perceptually Weighted (WP) SR technique that incorporates unequal weighting parameters in the cost function of iterative SR problems. The proposed approach is inspired by the unequal processing of the Human Visual System (HVS) to different local image features in an image. Simulation results show an enhanced reconstruction quality and faster convergence rates when applied to the MAP-based and FR-based SR schemes.
ContributorsSadaka, Nabil (Author) / Karam, Lina J (Thesis advisor) / Spanias, Andreas S (Committee member) / Papandreou-Suppappola, Antonia (Committee member) / Abousleman, Glen P (Committee member) / Goryll, Michael (Committee member) / Arizona State University (Publisher)
Created2011
Description
Photovoltaics (PV) is an important and rapidly growing area of research. With the advent of power system monitoring and communication technology collectively known as the "smart grid," an opportunity exists to apply signal processing techniques to monitoring and control of PV arrays. In this paper a monitoring system which provides real-time measurements of each PV module's voltage and current is considered. A fault detection algorithm formulated as a clustering problem and addressed using the robust minimum covariance determinant (MCD) estimator is described; its performance on simulated instances of arc and ground faults is evaluated. The algorithm is found to perform well on many types of faults commonly occurring in PV arrays. Among several types of detection algorithms considered, only the MCD shows high performance on both types of faults.
ContributorsBraun, Henry (Author) / Tepedelenlioğlu, Cihan (Thesis advisor) / Spanias, Andreas (Thesis advisor) / Turaga, Pavan (Committee member) / Arizona State University (Publisher)
Created2012
Description
Three-dimensional (3D) inductors with square, hexagonal and octagonal geometries have been designed and simulated in ANSYS HFSS. The inductors have been designed on Silicon substrate with through-hole via with different width, spacing and thickness. Spice modeling has been done in Agilent ADS and comparison has been made with results of custom excel based calculator and HFSS simulation results. Single ended quality factor was measured as 12.97 and differential ended quality factor was measured as 15.96 at a maximum operational frequency of 3.65GHz. The single ended and differential inductance was measured as 2.98nH and 2.88nH respectively at this frequency. Based on results a symmetric octagonal inductor design has been recommended to be used for application in RF biosensing. A system design has been proposed based on use of this inductor and principle of inductive sensing using magnetic labeling.
ContributorsAbbey, Hemanshu (Author) / Bakkaloglu, Bertan (Thesis advisor) / Kiaei, Sayfe (Committee member) / Goryll, Michael (Committee member) / Arizona State University (Publisher)
Created2012
Description
In this thesis, we consider the problem of fast and efficient indexing techniques for time sequences which evolve on manifold-valued spaces. Using manifolds is a convenient way to work with complex features that often do not live in Euclidean spaces. However, computing standard notions of geodesic distance, mean etc. can get very involved due to the underlying non-linearity associated with the space. As a result a complex task such as manifold sequence matching would require very large number of computations making it hard to use in practice. We believe that one can device smart approximation algorithms for several classes of such problems which take into account the geometry of the manifold and maintain the favorable properties of the exact approach. This problem has several applications in areas of human activity discovery and recognition, where several features and representations are naturally studied in a non-Euclidean setting. We propose a novel solution to the problem of indexing manifold-valued sequences by proposing an intrinsic approach to map sequences to a symbolic representation. This is shown to enable the deployment of fast and accurate algorithms for activity recognition, motif discovery, and anomaly detection. Toward this end, we present generalizations of key concepts of piece-wise aggregation and symbolic approximation for the case of non-Euclidean manifolds. Experiments show that one can replace expensive geodesic computations with much faster symbolic computations with little loss of accuracy in activity recognition and discovery applications. The proposed methods are ideally suited for real-time systems and resource constrained scenarios.
ContributorsAnirudh, Rushil (Author) / Turaga, Pavan (Thesis advisor) / Spanias, Andreas (Committee member) / Li, Baoxin (Committee member) / Arizona State University (Publisher)
Created2012
Description
The high cut-off frequency of deep sub-micron CMOS technologies has enabled the integration of radio frequency (RF) transceivers with digital circuits. However, the challenging point is the integration of RF power amplifiers, mainly due to the low breakdown voltage of CMOS transistors. Silicon-on-insulator (SOI) metal semiconductor field effect transistors (MESFETs) have been introduced to remedy the limited headroom concern in CMOS technologies. The MESFETs presented in this thesis have been fabricated on different SOI-CMOS processes without making any change to the standard fabrication steps and offer 2-30 times higher breakdown voltage than the MOSFETs on the same process. This thesis explains the design steps of high efficiency and wideband RF transmitters using the proposed SOI-CMOS compatible MESFETs. This task involves DC and RF characterization of MESFET devices, along with providing a compact Spice model for simulation purposes. This thesis presents the design of several SOI-MESFET RF power amplifiers operating at 433, 900 and 1800 MHz with ~40% bandwidth. Measurement results show a peak power added efficiency (PAE) of 55% and a peak output power of 22.5 dBm. The RF-PAs were designed to operate in Class-AB mode to minimize the linearity degradation. Class-AB power amplifiers lead to poor power added efficiency, especially when fed with signals with high peak to average power ratio (PAPR) such as wideband code division multiple access (W-CDMA). Polar transmitters have been introduced to improve the efficiency of RF-PAs at backed-off powers. A MESFET based envelope tracking (ET) polar transmitter was designed and measured. A low drop-out voltage regulator (LDO) was used as the supply modulator of this polar transmitter. MESFETs are depletion mode devices; therefore, they can be configured in a source follower configuration to have better stability and higher bandwidth that MOSFET based LDOs. Measurement results show 350 MHz bandwidth while driving a 10 pF capacitive load. A novel polar transmitter is introduced in this thesis to alleviate some of the limitations associated with polar transmitters. The proposed architecture uses the backgate terminal of a partially depleted transistor on SOI process, which relaxes the bandwidth and efficiency requirements of the envelope amplifier in a polar transmitter. The measurement results of the proposed transmitter demonstrate more than three times PAE improvement at 6-dB backed-off output power, compared to the traditional RF transmitters.
ContributorsGhajar, Mohammad Reza (Author) / Thornton, Trevor (Thesis advisor) / Aberle, James T., 1961- (Committee member) / Bakkaloglu, Bertan (Committee member) / Goryll, Michael (Committee member) / Arizona State University (Publisher)
Created2012
Description
Diabetic retinopathy (DR) is a common cause of blindness occurring due to prolonged presence of diabetes. The risk of developing DR or having the disease progress is increasing over time. Despite advances in diabetes care over the years, DR remains a vision-threatening complication and one of the leading causes of blindness among American adults. Recent studies have shown that diagnosis based on digital retinal imaging has potential benefits over traditional face-to-face evaluation. Yet there is a dearth of computer-based systems that can match the level of performance achieved by ophthalmologists. This thesis takes a fresh perspective in developing a computer-based system aimed at improving diagnosis of DR images. These images are categorized into three classes according to their severity level. The proposed approach explores effective methods to classify new images and retrieve clinically-relevant images from a database with prior diagnosis information associated with them. Retrieval provides a novel way to utilize the vast knowledge in the archives of previously-diagnosed DR images and thereby improve a clinician's performance while classification can safely reduce the burden on DR screening programs and possibly achieve higher detection accuracy than human experts. To solve the three-class retrieval and classification problem, the approach uses a multi-class multiple-instance medical image retrieval framework that makes use of spectrally tuned color correlogram and steerable Gaussian filter response features. The results show better retrieval and classification performances than prior-art methods and are also observed to be of clinical and visual relevance.
ContributorsChandakkar, Parag Shridhar (Author) / Li, Baoxin (Thesis advisor) / Turaga, Pavan (Committee member) / Frakes, David (Committee member) / Arizona State University (Publisher)
Created2012
Description
Recent advances in camera architectures and associated mathematical representations now enable compressive acquisition of images and videos at low data-rates. While most computer vision applications of today are composed of conventional cameras, which collect a large amount redundant data and power hungry embedded systems, which compress the collected data for further processing, compressive cameras offer the advantage of direct acquisition of data in compressed domain and hence readily promise to find applicability in computer vision, particularly in environments hampered by limited communication bandwidths. However, despite the significant progress in theory and methods of compressive sensing, little headway has been made in developing systems for such applications by exploiting the merits of compressive sensing. In such a setting, we consider the problem of activity recognition, which is an important inference problem in many security and surveillance applications. Since all successful activity recognition systems involve detection of human, followed by recognition, a potential fully functioning system motivated by compressive camera would involve the tracking of human, which requires the reconstruction of atleast the initial few frames to detect the human. Once the human is tracked, the recognition part of the system requires only the features to be extracted from the tracked sequences, which can be the reconstructed images or the compressed measurements of such sequences. However, it is desirable in resource constrained environments that these features be extracted from the compressive measurements without reconstruction. Motivated by this, in this thesis, we propose a framework for understanding activities as a non-linear dynamical system, and propose a robust, generalizable feature that can be extracted directly from the compressed measurements without reconstructing the original video frames. The proposed feature is termed recurrence texture and is motivated from recurrence analysis of non-linear dynamical systems. We show that it is possible to obtain discriminative features directly from the compressed stream and show its utility in recognition of activities at very low data rates.
ContributorsKulkarni, Kuldeep Sharad (Author) / Turaga, Pavan (Thesis advisor) / Spanias, Andreas (Committee member) / Frakes, David (Committee member) / Arizona State University (Publisher)
Created2012
Description
This research study examined the bilateral asymmetry found in muscle pairs including the right and left sides of the upper rectus abdominis, lower rectus abdominis, external oblique, and internal oblique in college-aged, apparently fit men and women. Bilateral symmetry was found using surface electromyography (EMG) during three core exercises: 1) ab-slides using paper plates (paper), 2) planks, and 3) ab-slides using a commercial AbSlide® roller device by comparing maximal voluntary contractions (MVCs) of the four muscles previously listed. This research analyzed the percentage of muscle activation during these exercises to each person’s MVC using Noraxon® software. Analysis found that asymmetry for each muscle group was present although there is no measure of clinical significance for symmetry scores of the core muscles yet.
Asymmetry scores were calculated for all three exercises. The exercise that produced the greatest absolute, average asymmetry score was the ab-slide using the roller device. The muscle that the greatest absolute asymmetry was found was the internal oblique. This means that during the three exercises and MVC, the greatest difference between right and left side pair muscles was observed in the internal obliques. The standard deviation of symmetry scores for all exercises and muscles was great as there was much variation in the skill levels in the participants of this study. Bilateral asymmetry was found by visually comparing the asymmetry scores. In conclusion, bilateral asymmetry was found in the core muscles of college-aged individuals during bilateral abdominal exercises.
Asymmetry scores were calculated for all three exercises. The exercise that produced the greatest absolute, average asymmetry score was the ab-slide using the roller device. The muscle that the greatest absolute asymmetry was found was the internal oblique. This means that during the three exercises and MVC, the greatest difference between right and left side pair muscles was observed in the internal obliques. The standard deviation of symmetry scores for all exercises and muscles was great as there was much variation in the skill levels in the participants of this study. Bilateral asymmetry was found by visually comparing the asymmetry scores. In conclusion, bilateral asymmetry was found in the core muscles of college-aged individuals during bilateral abdominal exercises.
ContributorsFavaro, Miguel Angel (Author) / Berger, Christopher (Thesis director) / Lorenz, Kent (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05
Description
This study examines cognitive planning in adolescents with Down syndrome (DS) following an 8-week assisted cycling therapy intervention. Forty-three participants were randomly assigned to assisted cycling (AC) (i.e., at least 30% faster than self-selected cadence accomplished by a motor), voluntary cycling (VC) (self-selected cadence), and no cycling (NC) control group. Both AC and VC rode a stationary bicycle three times/week, 30 minutes/session, for eight weeks in duration. Participants completed cognitive testing that assessed cognitive planning at the beginning (i.e., pretest) and end (i.e., posttest) of the 8-week intervention. Consistent with our hypothesis, the results showed that cognitive planning improved following eight weeks of cycling for the AC group. The same results were not seen for individuals in the VC or NC groups. Our results suggest that assisted cycling therapy may induce permanent changes in the prefrontal cortex in adolescents with DS.
ContributorsMillar, Kelsey Leann (Author) / Ringenbach, Shannon (Thesis director) / Amazeen, Eric (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2015-05