Matching Items (683)
141491-Thumbnail Image.png
Description

Background: Children with autism have often been reported to have gastrointestinal problems that are more frequent and more severe than in children from the general population.

Methods: Gastrointestinal flora and gastrointestinal status were assessed from stool samples of 58 children with Autism Spectrum Disorders (ASD) and 39 healthy typical children of similar ages.

Background: Children with autism have often been reported to have gastrointestinal problems that are more frequent and more severe than in children from the general population.

Methods: Gastrointestinal flora and gastrointestinal status were assessed from stool samples of 58 children with Autism Spectrum Disorders (ASD) and 39 healthy typical children of similar ages. Stool testing included bacterial and yeast culture tests, lysozyme, lactoferrin, secretory IgA, elastase, digestion markers, short chain fatty acids (SCFA's), pH, and blood presence. Gastrointestinal symptoms were assessed with a modified six-item GI Severity Index (6-GSI) questionnaire, and autistic symptoms were assessed with the Autism Treatment Evaluation Checklist (ATEC).

Results: Gastrointestinal symptoms (assessed by the 6-GSI) were strongly correlated with the severity of autism (assessed by the ATEC), (r = 0.59, p < 0.001). Children with 6-GSI scores above 3 had much higher ATEC Total scores than those with 6-GSI-scores of 3 or lower (81.5 +/- 28 vs. 49.0 +/- 21, p = 0.00002).
Children with autism had much lower levels of total short chain fatty acids (-27%, p = 0.00002), including lower levels of acetate, proprionate, and valerate; this difference was greater in the children with autism taking probiotics, but also significant in those not taking probiotics. Children with autism had lower levels of species of Bifidobacter (-43%, p = 0.002) and higher levels of species of Lactobacillus (+100%, p = 0.00002), but similar levels of other bacteria and yeast using standard culture growth-based techniques. Lysozyme was somewhat lower in children with autism (-27%, p = 0.04), possibly associated with probiotic usage. Other markers of digestive function were similar in both groups.

Conclusions: The strong correlation of gastrointestinal symptoms with autism severity indicates that children with more severe autism are likely to have more severe gastrointestinal symptoms and vice versa. It is possible that autism symptoms are exacerbated or even partially due to the underlying gastrointestinal problems. The low level of SCFA's was partly associated with increased probiotic use, and probably partly due to either lower production (less sacchrolytic fermentation by beneficial bacteria and/or lower intake of soluble fiber) and/or greater absorption into the body (due to longer transit time and/or increased gut permeability).

ContributorsAdams, James (Author) / Johansen, Leah (Author) / Powell, Linda (Author) / Quig, David (Author) / Rubin, Robert A. (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2011-03-16
141495-Thumbnail Image.png
Description

The electronic structure of eight zinc-centered porphyrin macrocyclic molecules are investigated using density functional theory for ground-state properties, time-dependent density functional theory (TDDFT) for excited states, and Franck-Condon (FC) analysis for further characterization of the UV-vis spectrum. Symmetry breaking was utilized to find the lowest energy of the excited states

The electronic structure of eight zinc-centered porphyrin macrocyclic molecules are investigated using density functional theory for ground-state properties, time-dependent density functional theory (TDDFT) for excited states, and Franck-Condon (FC) analysis for further characterization of the UV-vis spectrum. Symmetry breaking was utilized to find the lowest energy of the excited states for many states in the spectra. To confirm the theoretical modeling, the spectroscopic result from zinc phthalocyanine (ZnPc) is used to compare to the TDDFT and FC result. After confirmation of the modeling, five more planar molecules are investigated: zinc tetrabenzoporphyrin (ZnTBP), zinc tetrabenzomonoazaporphyrin (ZnTBMAP), zinc tetrabenzocisdiazaporphyrin (ZnTBcisDAP), zinc tetrabenzotransdiazaporphyrin (ZnTBtransDAP), and zinc tetrabenzotriazaporphyrin (ZnTBTrAP). The two latter molecules are then compared to their phenylated sister molecules: zinc monophenyltetrabenzotriazaporphyrin (ZnMPTBTrAP) and zinc diphenyltetrabenzotransdiazaporphyrin (ZnDPTBtransDAP). The spectroscopic results from the synthesis of ZnMPTBTrAP and ZnDPTBtransDAP are then compared to their theoretical models and non-phenylated pairs. While the Franck-Condon results were not as illuminating for every B-band, the Q-band results were successful in all eight molecules, with a considerable amount of spectral analysis in the range of interest between 300 and 750 nm. The π-π* transitions are evident in the results for all of the Q bands, while satellite vibrations are also visible in the spectra. In particular, this investigation finds that, while ZnPc has a D4h symmetry at ground state, a C4v symmetry is predicted in the excited-state Q band region. The theoretical results for ZnPc found an excitation energy at the Q-band 0-0 transition of 1.88 eV in vacuum, which is in remarkable agreement with published gas-phase spectroscopy, as well as our own results of ZnPc in solution with Tetrahydrofuran that are provided in this paper.

ContributorsTheisen, Rebekah (Author) / Huang, Liang (Author) / Fleetham, Tyler (Author) / Adams, James (Author) / Li, Jian (Author) / Ira A. Fulton Schools of Engineering (Contributor)
Created2015-03-07
Description
The Tale of the Tigers is a children’s picture book in which a tiger named Guava is transported from his world of Serenia to our world. In an attempt to find someone to help him with this situation, Guava meets another tiger named Papaya. After having his prey scared away

The Tale of the Tigers is a children’s picture book in which a tiger named Guava is transported from his world of Serenia to our world. In an attempt to find someone to help him with this situation, Guava meets another tiger named Papaya. After having his prey scared away by Guava, Papaya begins to explain the different hardships and dangers that tigers face in their natural habitat. Papaya also teaches Guava about the different programs and activities that humans have been doing to help increase and restore tiger populations. At the end of the story, Guava returns to his world and spreads awareness to those that live in Serenia about how tigers are threatened in other places and what’s being done to help them. Papaya uses basic ecological concepts to explain the importance of tigers in their ecosystem. These concepts include habitat loss, trophic levels, landscape fragmentation, and poaching. The story also incorporates different conservation methods, including captive breeding and the use of camera traps.
ContributorsMooney, Lena (Author) / Jesse, Lewis (Thesis director) / Meloy, Elizabeth (Committee member) / College of Integrative Sciences and Arts (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
131445-Thumbnail Image.png
Description
Food provides nutrients and sustenance that are essential to life. Humans rely on food to fuel our thoughts and actions. However, food isn’t just a source of energy; it’s a fundamental part of culture and connection. Simply sharing a meal with someone can build teamwork and create

Food provides nutrients and sustenance that are essential to life. Humans rely on food to fuel our thoughts and actions. However, food isn’t just a source of energy; it’s a fundamental part of culture and connection. Simply sharing a meal with someone can build teamwork and create a bond. Throughout this short memoir, I explored the ways in which food creates a connection across language and cultural barriers through reflection on specific experiences that I had in India, Uganda, and South Africa. While my experiences in each of these three countries were vastly different, there was one defining theme that brought them together: food. This memoir uses mixed media (personal reflection, research, recipes, and photos) to connect the three different international experiences. Reflection on my own family traditions and history bridges the gap between my upbringing and my interactions with people while spending time abroad. Popular recipes from each of the three countries are mixed into the personal reflection, showing how preparing food in a different geographic location can change the experience of preparation and eating. In addition to personal experience, included is a synthesis of research done on the effects of sharing a plate or a meal on negotiations tactics, how eating the same food increases trust, the ways in which food sharing is an act of social intimacy, and how it can build community. Food is an important part of family connection, a tool in many rituals such as Sunday dinners or breaking bread, a critical aspect of many religions, and is tied to the celebration of both birth and death in cultures around the globe. We all need to eat; food is the great commonality among people.
ContributorsRivard-Lentz, Haley Marie Anne (Co-author) / Rivard-Lentz, Haley (Co-author) / Fette, Donald (Thesis director) / Jacobs, Mark (Committee member) / School of Sustainability (Contributor) / School of Public Affairs (Contributor) / Watts College of Public Service & Community Solut (Contributor) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
133428-Thumbnail Image.png
Description
Optical Communications are at a high point of interest by the space engineering community. After successful projects like the Lunar Laser Communications Demonstration (LLCD), NASA has become interested in augmenting their current Deep Space Network (DSN) with optical communication links. One such link is Deep Space Optical Communications (DSOC) which

Optical Communications are at a high point of interest by the space engineering community. After successful projects like the Lunar Laser Communications Demonstration (LLCD), NASA has become interested in augmenting their current Deep Space Network (DSN) with optical communication links. One such link is Deep Space Optical Communications (DSOC) which will be launching with the Psyche mission. To gain a full understanding of the advantages of this network, this thesis will go over the history and benefits of optical communications both on Earth and in space. This thesis will then go in depth on NASAs DSOC project through an algorithmic implementation of the communications channel.
ContributorsHorton, Paul Alexander (Author) / Mauskopf, Philip (Thesis director) / Sandy, Douglas (Committee member) / Martin, Thomas (Committee member) / Software Engineering (Contributor) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This project, Building the Backdrop, Expanding Perspectives on Sustainability, is a sculpture of a desert sunset that seeks to explore important sustainability issues and highlight the beauty in sustainable practices. Constructed for an honors thesis project at Arizona State University, the primary medium used was cardboard repurposed from package deliveries

This project, Building the Backdrop, Expanding Perspectives on Sustainability, is a sculpture of a desert sunset that seeks to explore important sustainability issues and highlight the beauty in sustainable practices. Constructed for an honors thesis project at Arizona State University, the primary medium used was cardboard repurposed from package deliveries to bring attention to modern overconsumption of packaging materials and showcase our ability to give new life to traditionally single use materials. I invite you to interact with the piece by sharing photos of yourself in front of it to help spread its message and exploring the resources shared along with the sculpture.
ContributorsSandoval, Nicole (Author) / Hines, Taylor (Thesis director) / Meissinger, Ellen (Committee member) / Barrett, The Honors College (Contributor) / Department of Supply Chain Management (Contributor) / Dean, W.P. Carey School of Business (Contributor) / College of Integrative Sciences and Arts (Contributor)
Created2024-05
Description
A guidebook meant to be used by the leadership of the club Poly Purrs. It includes definitions of key terms as well as literature-backed discussion of free-roaming cats in general. The second half of it is advice and information drawn from my own experience with the cat population on the

A guidebook meant to be used by the leadership of the club Poly Purrs. It includes definitions of key terms as well as literature-backed discussion of free-roaming cats in general. The second half of it is advice and information drawn from my own experience with the cat population on the Polytechnic campus.
ContributorsWiese, Alexa (Author) / Murphree, Julie (Thesis director) / Gallaway, Cynthia (Committee member) / Barrett, The Honors College (Contributor) / College of Integrative Sciences and Arts (Contributor)
Created2024-05
Description
We discuss the intricate and puzzling concept of quantum entanglement, and not only define it but also consider the implications of the behaviors of entangled particles. The ability of these particles to provide instantaneous information about their entangled counterparts sparked a debate among physicists as to whether or not these particles had

We discuss the intricate and puzzling concept of quantum entanglement, and not only define it but also consider the implications of the behaviors of entangled particles. The ability of these particles to provide instantaneous information about their entangled counterparts sparked a debate among physicists as to whether or not these particles had definite quantities before measurement, and whether or not their behaviors could be explained by a local hidden-variables theorem. Mermin’s gedanken demonstration for a two-particle entangled system is introduced, as well as Bell’s inequality, and an explanation of how a pair of two entangled particles violate this inequality. Additionally, we also discuss various experimental verifications that were able to use Bell’s inequality to verify the expected quantum mechanical results for their entangled systems.
ContributorsDavis, Elsie (Author) / Foy, Joseph (Thesis director) / Hines, Taylor (Committee member) / Barrett, The Honors College (Contributor) / College of Integrative Sciences and Arts (Contributor)
Created2024-05
Description
Terrestrial hermit crabs serve an incredibly important ecological role in seed dispersal and as decomposers along coastal shorelines. They have also become quite popular in the commercial pet trade, with one species, Coenobita clypeatus, being particularly favored. Typically, these hermit crabs are easily captured and removed from the wild with

Terrestrial hermit crabs serve an incredibly important ecological role in seed dispersal and as decomposers along coastal shorelines. They have also become quite popular in the commercial pet trade, with one species, Coenobita clypeatus, being particularly favored. Typically, these hermit crabs are easily captured and removed from the wild with little protection in their native ranges. In Hermitage Bay, Tobago, there is little information about the population numbers, composition, shell preference, and substrate preference of C. clypeatus in their native habitat. In this study, we estimated population size, gastropod shell preferences, and substrate preference conditions when clustering. We conducted mark re-capture surveys in March, July, and December 2023 and collected morphological data from captured hermit crabs. Our results indicate that the estimated population was highest in July, with the variation being significant when using the Schnabel mark re-capture estimation formula. The most common overall shell type, Columbella mercatoria (West Indian Dove Shell), was prevalent among the smaller sized, younger hermit crabs; while the larger hermit crabs preferred Cittarium pica (West Indian Top Shell). The most preferred substrate for these terrestrial hermit crabs were areas with a mixture of sand and dirt, with high amounts of vegetation and leaf waste and low amounts of human litter. These results suggest a predominantly young population and that beach cleanups should focus on removing human litter entirely, while leaving leaf waste and other fallen logs and branches and not using the collected decomposing plant matter for bonfires. This can help maintain a healthy hermit crab population that continues to benefit the coastlines in Tobago as well as other ecosystems.
ContributorsLindteigen, Amy (Author) / Briggs, Georgette (Thesis director) / Mohammed, Ryan (Committee member) / Barrett, The Honors College (Contributor) / College of Integrative Sciences and Arts (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2024-05
Description
Chisholm’s contrary-to-duty paradox raises important questions for formulating instances of conditional obligation. Angelika Kratzer is one linguist whose theories offer some solutions to these questions; more generally, she provides theories for how we should represent modals, conditionals, and other features of language in terms of functions. Though her theories are

Chisholm’s contrary-to-duty paradox raises important questions for formulating instances of conditional obligation. Angelika Kratzer is one linguist whose theories offer some solutions to these questions; more generally, she provides theories for how we should represent modals, conditionals, and other features of language in terms of functions. Though her theories are incredibly useful, they do not adequately represent the Chisholm scenario as a whole. In this paper, I attempt to address this shortcoming in her theory. First, I present and explain some of Kratzer’s main ideas. Then, I explain how her theory offers a solution to Chisholm’s Paradox, and examine a shortcoming of her theory as presented– specifically, the fact that her theory does not account for the importance of different norms in relation to each other. Finally, with the Chisholm situation as a backdrop, I offer my own contribution to her theory. Namely, I propose assigning an importance “score” to each norm, and factoring that “score” into the machinery of Kratzer’s theory.
ContributorsBrooks, Elizabeth (Author) / nair, shyam (Thesis director) / Pinillos, Angel (Committee member) / Barrett, The Honors College (Contributor) / College of Integrative Sciences and Arts (Contributor) / Historical, Philosophical & Religious Studies, Sch (Contributor)
Created2024-05