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Description
The effects of over-the-counter drug (OTC) use on college students' health has been debated in the field of psychology with researchers arguing that poor sleep quality among college students is the result of polysubstance use. However, this explanation is not a foregone conclusion. These researchers have not adequately addressed the

The effects of over-the-counter drug (OTC) use on college students' health has been debated in the field of psychology with researchers arguing that poor sleep quality among college students is the result of polysubstance use. However, this explanation is not a foregone conclusion. These researchers have not adequately addressed the issue poor sleep quality among college students and its relationship to polysubstance use. This is an important issue because prolonged unsupervised OTC drug use and poor sleep quality can impact long-term health and lessen students' likelihood of being successful in college. This paper addresses the issue of OTC drug use with special attention to sleep quality. Pittsburgh Sleep Quality Index Scores were collected to assess subjective sleep quality and its relationship to OTC drug use. Several other risk factors including binge drinking, marijuana use, and illicit drug use were also accounted for in this model. This study argues that, although the current literature suggests that poor sleep quality is the effect of drug use rather than the cause; the relationships between these factors are still unclear. This study aims to fill a gap in the college drug use literature by establishing a relationship between poor sleep quality and OTC drug use in a college sample.
ContributorsLara, Gustavo (Author) / Vargas, Perla (Thesis advisor) / Burleson, Mary (Committee member) / Robles-Sotelo, Elias (Committee member) / Arizona State University (Publisher)
Created2014
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Description
Sleep is essential for physical and psychological health. Sleep has also been linked to the daily patterns of key stress-responsive physiological systems, specifically the hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system (ANS). Extant research examining sleep and diurnal patterns of cortisol, the primary end product of the HPA axis, is

Sleep is essential for physical and psychological health. Sleep has also been linked to the daily patterns of key stress-responsive physiological systems, specifically the hypothalamic-pituitary-adrenal (HPA) axis and autonomic nervous system (ANS). Extant research examining sleep and diurnal patterns of cortisol, the primary end product of the HPA axis, is inconsistent. Moreover, it is not clear how specific aspects of sleep behavior (e.g., sleep duration, sleep quality, sleep variability) are related to specific components of diurnal cortisol rhythms. Salivary alpha-amylase (sAA) has been recognized as a surrogate marker of ANS activity, but limited research has explored relations between sleep and sAA diurnal rhythms. The current study utilized a modified ecological momentary assessment protocol to examine within- and between-person relations between multiple facets of sleep behavior using multiple methods (e.g., subjective report, actigraphy) and salivary cortisol and sAA. First year college students (N = 76) provided saliva samples and diary entries five times per day over the course of three days. Sleep was assessed via questionnaire, through daily diaries, and monitored objectively using actigraphy over a four day period. Between-person results revealed that shorter average sleep duration and greater sleep variability was related to lower levels of waking cortisol and flatter diurnal slopes across the day. Within-person results revealed that on nights when individuals slept for shorter durations than usual they also had lower levels of waking cortisol the next day. Sleep was not related to the cortisol awakening response (CAR) or diurnal patterns of sAA, in either between-person or within-person analyses. However, typical sleep behaviors measured via questionnaire were related to waking levels of sAA. Overall, this study provides a greater understanding of how multiple components of sleep, measured in naturalistic environments, is related to cortisol and sAA diurnal rhythms, and how day-to-day, within-person changes in sleep duration contribute to daily variations in cortisol.
ContributorsVan Lenten, Scott Alan (Author) / Doane, Leah D (Thesis advisor) / Granger, Douglas A. (Committee member) / Infurna, Frank J. (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Understanding how interpersonal relationships, such as parenting and sibling relationships, may contribute to early sleep development is important, as early sleep dysregulation has been shown to impact later sleep behavior (Sadeh & Anders, 1993), as well as cognitive and behavioral functioning (Gregory et al., 2006; Soffer-Dudek et al., 2011). In

Understanding how interpersonal relationships, such as parenting and sibling relationships, may contribute to early sleep development is important, as early sleep dysregulation has been shown to impact later sleep behavior (Sadeh & Anders, 1993), as well as cognitive and behavioral functioning (Gregory et al., 2006; Soffer-Dudek et al., 2011). In addition, twin studies provide an optimal opportunity to estimate genetic and environmental contributions to parenting, sibling relationships and child sleep, as they are influenced by both genetic and contextual factors. As such, the current thesis examined whether parental punitive discipline and sibling conflict were associated with child sleep duration, dysregulation and daytime sleepiness at 12 months, 30 months, and five years in a longitudinal sample of young twins recruited through birth records (Lemery-Chalfant et al., 2013). Mixed model regression analyses and quantitative behavioral genetic models (univariate and bivariate) were conducted to explore bidirectional relations and estimate genetic and environmental contributions to parental punitive punishment, sibling conflict and child sleep parameters. Sleep duration and dysregulation showed stability over time. Parental punitive discipline did not predict concurrent or future sleep parameters, nor were there bidirectional relations between punitive discipline and child sleep behaviors. Greater sibling conflict at five years was associated with shorter concurrent child sleep duration and greater daytime sleepiness, suggesting that sibling conflict may be a critical interpersonal stressor that negatively impacts child sleep. Shared environmental factors also accounted for the greatest proportion of the covariance between sibling conflict and sleep duration and daytime sleepiness at five years. These findings hold promise for sleep and sibling interaction interventions, including educating parents about fostering positive sibling relations and teaching caregivers to utilize specific parenting behaviors that may encourage better child sleep behaviors (e.g., establishing bedtime routines). Future studies should aim to understand the nuances of associations between family relationships (like punitive discipline and sibling conflict) and child sleep, as well as other explore person- and family-level factors, such as child negative emotions and parenting, that may influence associations between family relationships and child sleep.
ContributorsBreitenstein, Reagan Styles (Author) / Doane, Leah D (Thesis advisor) / Lemery, Kathryn (Committee member) / Bradley, Robert (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Sleep is an essential human function. Modern day society has made it so that sleep is prioritized less and less. Professionals in critical positions such as doctors, nurses, and emergency medical technicians can often have hectic schedules that are unforgiving toward sleep due to the increase in shift work that

Sleep is an essential human function. Modern day society has made it so that sleep is prioritized less and less. Professionals in critical positions such as doctors, nurses, and emergency medical technicians can often have hectic schedules that are unforgiving toward sleep due to the increase in shift work that dominates these fields. Sleep deficits can have detrimental effects on one’s psyche and mood. Depression and anxiety both have high comorbidity rates with insomnia because of sleeping deficits. Transdermal Electrical Nerve Stimulation (TENS) offers a potential solution to improving sleep quality and mood by modulating the ascending reticular activating system (RAS). This system starts in the anterior portion of the head with trigeminal nerve branches and is stimulated using a 500-550 Hz waveform.

In this experiment Positive Affect and Negative Affect Schedule (PANAS) scores are recorded daily to monitor mood differences between pre and post treatment (TENS vs Sham). PANAS scores were found to be insignificant between groups. Pittsburgh Sleep Quality Index (PSQI), and Fitbit were chosen to study perceived sleep, and objective sleep. Both PSQI, and Fitbit found insignificant differences between TENS and Sham. Finally, the Beck Depression and Beck Anxiety Inventories were administered weekly to determine if there are immediate changes to depressive and anxiety symptom, after a week of treatment (TENS vs Sham). A significant difference was found between the pre and post of the TENS treatment group. The TENS group was not found to be significantly different from Sham, potentially the result of a placebo effect. These results were found with n=10 participants in the TENS treatment group and n=6 in the sham group.
ContributorsUdave, Ceasar (Author) / Tyler, William J (Thesis advisor) / Buneo, Christopher (Committee member) / Wyckoff, Sarah (Committee member) / Arizona State University (Publisher)
Created2018
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Description
The transition out of high school is a major milestone for adolescents as they earn greater autonomy and responsibilities. An estimated 69.2% of adolescents enroll in higher education immediately following high school completion, including increasing numbers of Latino adolescents (National Center for Education Statistics, 2016). Integrative model (García Coll et

The transition out of high school is a major milestone for adolescents as they earn greater autonomy and responsibilities. An estimated 69.2% of adolescents enroll in higher education immediately following high school completion, including increasing numbers of Latino adolescents (National Center for Education Statistics, 2016). Integrative model (García Coll et al., 1996) suggests a need for research on promotive and protective contextual factors for ethnic minority children and adolescents. Guided by the model, the proposed research will explore a salient Latino cultural value, familism, and family communication as predictors of changes in depressive symptoms from high school to university among Latino adolescents (N = 209; 35.6% male; Mage=17.59, SD=.53). Furthermore, sleep, a key bioregulatory mechanism, was explored as a potential moderator of these processes (Dahl & El-Sheikh, 2007). On average, familism values were not associated with college depressive symptoms, but family communication was significantly negatively associated with college depressive symptoms. Neither sleep duration nor sleep problems significantly moderated the association between familism values and college depressive symptom. Patterns were similar for family communication. The interaction between sleep problems and familism-support values were significantly associated with college depressive symptoms. However, when simple slopes were probed, none were significant.
ContributorsPark, HyeJung (Author) / Doane, Leah (Thesis advisor) / Infurna, Frank (Committee member) / Updegraff, Kimberly (Committee member) / Arizona State University (Publisher)
Created2019
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Description
The present study tested 1) whether children’s bedtimes, wake times, and sleep

durations change as they transition into kindergarten (TtoK), 2) if changes to children’s

sleep schedules were contingent on their pre-kindergarten (T1) napping status and if T1

bedtimes were related to fall (T2) and spring (T3) bedtimes and durations, and 3) whether

T1

The present study tested 1) whether children’s bedtimes, wake times, and sleep

durations change as they transition into kindergarten (TtoK), 2) if changes to children’s

sleep schedules were contingent on their pre-kindergarten (T1) napping status and if T1

bedtimes were related to fall (T2) and spring (T3) bedtimes and durations, and 3) whether

T1 sleep, changes to sleep from T1 to T2, and concurrent sleep quality were related to

academic achievement and participation in 51 kindergarteners. It was hypothesized that

1) wake times would be earlier and sleep duration would be shorter during kindergarten

(T2 and T3) than at T1, 2) children who napped at T1 would go to bed later and have

shorter sleep duration than their non-napping peers and T1 bedtimes would be positively

associated with T2 and T3 bedtimes and negatively associated with T2 and T3 durations,

and 3) more optimal sleep (e.g., consolidated, consistent, and high quality) would be

positively related to academic achievement and participation. Parents reported on

children’s bedtimes, wake times, and nap lengths during T1, T2, and T3. During T3

children wore actigraphs for five consecutive school nights and completed the Woodcock

Johnson tests of achievement (WJ-III). Teachers also reported on children’s participation

in the classroom during T3. Results demonstrated that bedtimes and wake times were

earlier at T2 and T3 than T1. Duration was shorter at T2 and T3 than T1. Additionally,

napping was unrelated to bedtimes and durations, but T1 bedtime was positively related

to T2 and T3 bedtimes and negatively related to T2 and T3 durations. Finally, T1 nap

length, change in bedtimes, and Actigraphy duration were negatively related to

participation. Actigraphy onset variability was positively related to participation.
ContributorsBerger, Rebecca Hilary (Author) / Valiente, Carlos (Thesis advisor) / Eisenberg, Nancy (Committee member) / Doane, Leah (Committee member) / Arizona State University (Publisher)
Created2015
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Description
Affiliative touch, such as physical affection between relationship partners, activates neural systems associated with reward, relaxation, and attachment. Co-sleeping is a common practice among romantic partners, and the social context of sleep is linked to well-being. The effect of touch during sleep, however, remains largely untested. As a first

Affiliative touch, such as physical affection between relationship partners, activates neural systems associated with reward, relaxation, and attachment. Co-sleeping is a common practice among romantic partners, and the social context of sleep is linked to well-being. The effect of touch during sleep, however, remains largely untested. As a first study, 210 married couples were asked how much they generally touched during sleep and how important it was for them to touch during sleep. I hypothesized that perceptions of more spousal touch during sleep, as well as greater importance placed on that touch, would be associated with better quality of sleep. Given the strong links between touch and attachment, and previous findings of poor sleep associated with attachment anxiety, these effects were expected to be greatest among spouses higher in attachment anxiety (who might benefit most from a sense of security arising from touch). Separate regression analyses were run for husbands and wives, controlling for affective symptoms of depression (which were significant predictors of poor sleep for both spouses). For both spouses, higher reports of amount and importance of touch during sleep predicted better quality of sleep. For wives, the predicted interaction was significant, but in the opposite direction: Reported amount and importance of spousal touch during sleep was positively related to sleep quality only among those with lower attachment anxiety, whereas it was unrelated among those with higher attachment anxiety. Higher attachment anxiety also was related to worse sleep among wives, but not husbands. It may be the case that wives who are lowest in attachment anxiety may feel more comfortable when being touched by their partners. As a result, they may touch more often, place more importance on touch, and be more likely to experience rewards of touch such as better sleep quality. The findings lend support to the idea that social touch can serve a regulatory function, even during sleep.
ContributorsShahid, Shiza (Author) / Burleson, Mary H (Thesis advisor) / Roberts, Nicole A. (Committee member) / Nanez, Jose (Committee member) / Arizona State University (Publisher)
Created2017
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Description
Physical activity, sedentary behaviors, and sleep are often associated with cardiometabolic biomarkers commonly found in metabolic syndrome. These relationships are well studied, and yet there are still questions on how each activity may affect cardiometabolic biomarkers. The objective of this study was to examine data from the BeWell24 studies to

Physical activity, sedentary behaviors, and sleep are often associated with cardiometabolic biomarkers commonly found in metabolic syndrome. These relationships are well studied, and yet there are still questions on how each activity may affect cardiometabolic biomarkers. The objective of this study was to examine data from the BeWell24 studies to evaluate the relationship between objectively measured physical activity and sedentary behaviors and cardiometabolic biomarkers in middle age adults, while also determining if sleep quality and duration mediates this relationship. A group of inactive participants (N = 29, age = 52.1 ± 8.1 years, 38% female) with increased risk for cardiometabolic disease were recruited to participate in BeWell24, a trial testing the impact of a lifestyle-based, multicomponent smartphone application targeting sleep, sedentary, and more active behaviors. During baseline, interim (4 weeks), and posttest visits (8 weeks), biomarker measurements were collected for weight (kg), waist circumference (cm), glucose (mg/dl), insulin (uU/ml), lipids (mg/dl), diastolic and systolic blood pressures (mm Hg), and C reactive protein (mg/L). Participants wore validated wrist and thigh sensors for one week intervals at each time point to measure sedentary behavior, physical activity, and sleep outcomes. Long bouts of sitting time (>30 min) significantly affected triglycerides (beta = .15 (±.07), p<.03); however, no significant mediation effects for sleep quality or duration were present. No other direct effects were observed between physical activity measurements and cardiometabolic biomarkers. The findings of this study suggest that reductions in long bouts of sitting time may support reductions in triglycerides, yet these effects were not mediated by sleep-related improvements.
ContributorsLanich, Boyd (Author) / Buman, Matthew (Thesis advisor) / Ainsworth, Barbara (Committee member) / Huberty, Jennifer (Committee member) / Arizona State University (Publisher)
Created2017
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Description
How early life is experienced and perceived can greatly affect mental and physical health outcomes. An individual is greatly influenced by their first models of what social relationships look and feel like, and with time also learn how to survive when less favorable social experiences occur. The lessons learned may

How early life is experienced and perceived can greatly affect mental and physical health outcomes. An individual is greatly influenced by their first models of what social relationships look and feel like, and with time also learn how to survive when less favorable social experiences occur. The lessons learned may lead to healthy problem solving and resilience, or it may lead to unhealthy problem-solving habits that hinder well-being. Anxious thoughts and other mental health symptoms may accompany an individual long-term and hinder an essential need for a healthy life. The first main purpose of this thesis is to examine the impact of Adverse Childhood Experiences (ACEs) on mental health (anxiety symptoms), and on sleep quality (an essential need). The second purpose of my thesis is to investigate the impact of genetics on resilience, specifically, the mu-opioid receptor gene. The first hypothesis proposed ACEs that were perceived as more traumatic and occurred more frequently would be associated with more poor sleep quality symptoms. The second hypothesis predicted that anxiety symptoms would mediate the association. The third hypothesis (exploratory) suggested that an individual’s alleles for the mu-opioid receptor gene would moderate the mediation pathway. The study was conducted with 318 participants between the ages of 18 and 35 years old. The study demonstrated a direct effect for ACEs and sleep. Anxiety mediated the association between ACEs (exposure and severity) and sleep (insomnia, quality, sleepiness), suggesting that ACEs possibly increase feelings of anxiety which, in turn, lead to worse sleep outcomes. Finally, the moderated-mediation model with OPRM1 as the moderator, was not significant for the mediation pathway A; however, there was a significant interaction with anxiety and sleep symptoms.
ContributorsBailey, Elise (Author) / Mickelson, Kristin (Thesis advisor) / Burleson, Mary (Committee member) / Petrov, Megan (Committee member) / Arizona State University (Publisher)
Created2022
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Description
Chronic pain is common during childhood and has negative immediate and long-term implications for physical and mental health. Prior research points to physical activity and sleep as protective health-promoting behaviors predicting lower chronic pain intensity and disability during adulthood. No study has yet examined the interaction of physical activity and

Chronic pain is common during childhood and has negative immediate and long-term implications for physical and mental health. Prior research points to physical activity and sleep as protective health-promoting behaviors predicting lower chronic pain intensity and disability during adulthood. No study has yet examined the interaction of physical activity and sleep parameters in prediction of chronic pain in a community sample of children. Guided by the biopsychosocial model of pediatric chronic pain, this study explored objectively assessed physical activity and sleep patterns at age 8 as predictors of childhood chronic pain at age 9 in a racially/ethnically and socioeconomically diverse sample of 896 twins participating in the longitudinal Arizona Twin Project. It was hypothesized that parameters of physical activity levels and sleep health would independently predict chronic pain one year later, and that sleep parameters would moderate the association between physical activity and chronic pain. Monthly chronic pain was common, with 57.1% of participants reporting at least one pain location. Headaches, stomachaches, and backaches were the most frequent chronic pain presentations. Participants exceeded physical activity guidelines but did not meet sleep recommendations for their age group. Multilevel modeling analyses revealed that physical activity and sleep parameters at age 8 did not predict chronic pain one year later, and that sleep parameters did not moderate the associations between physical activity and chronic pain. The present study provides evidence that the associations between objectively assessed physical activity and sleep and chronic pain are not yet evident during middle childhood in this community sample compared to patient samples who have existing pain, suggesting that these health behaviors may play distinct roles in pain development versus pain management. They also point to the need to pinpoint the time frame during which these health behaviors become relevant and potentially interact to predict chronic pain development and maintenance. Longitudinal research tracking these health behaviors and pain using both subjective and objective methods as children transition into and through adolescence can help to identify optimal developmental stages at which to target prevention and intervention efforts to promote long term health.
ContributorsBartsch, Eva Marie (Author) / Davis, Mary C (Thesis advisor) / Doane, Leah D (Committee member) / Lemery-Chalfant, Kathryn (Committee member) / Arizona State University (Publisher)
Created2023