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- Creators: Barrett, The Honors College
- Creators: School of Nutrition and Health Promotion
Description
This paper focuses on the current use of complementary medicine in Oncology. First, it reviews the general trends in the rise of complementary therapies in the United States and look at the organizations responsible for the advancement of research. Next reviewed is the specific use of complementary medicine in cancer prevention, during treatment, and post-treatment therapy for increased quality of life. There are many modalities used in the management of this disease including yoga, tai chi chuan, botanicals, probiotics and meditation practices. Each of these therapies has their own unique benefits and are used at different stages of disease prevention and treatment.
ContributorsBalcerzak, Erin Mary (Author) / Larkey, Linda (Thesis director) / Hosley, Brenda (Committee member) / Bucho-Gonzalez, Julie (Committee member) / Barrett, The Honors College (Contributor) / School of Nutrition and Health Promotion (Contributor)
Created2013-05
Description
Adaptive therapy utilizes competitive interactions between resistant and sensitive cells by keeping some sensitive cells to control tumor burden with the aim of increasing overall survival and time to progression. The use of adaptive therapy to treat breast cancer, ovarian cancer, and pancreatic cancer in preclinical models has shown significant results in controlling tumor growth. The purpose of this thesis is to draft a protocol to study adaptive therapy in a preclinical model of breast cancer on MCF7, estrogen receptor-positive, cells that have evolved resistance to fulvestrant and palbociclib (MCF7 R). In this study, we used two protocols: drug dose adjustment and intermittent therapy. The MCF7 R cell lines were injected into the mammary fat pads of 11-month-old NOD/SCID gamma (NSG) mice (18 mice) which were then treated with gemcitabine.<br/>The results of this experiment did not provide complete information because of the short-term treatments. In addition, we saw an increase in the tumor size of a few of the treated mice, which could be due to the metabolism of the drug at that age, or because of the difference in injection times. Therefore, these adaptive therapy protocols on hormone-refractory breast cancer cell lines will be repeated on young, 6-week old mice by injecting the cell lines at the same time for all mice, which helps the results to be more consistent and accurate.
ContributorsConti, Aviona (Author) / Maley, Carlo (Thesis director) / Blattman, Joseph (Committee member) / Seyedi, Sareh (Committee member) / School of Life Sciences (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
Yoga has become one of the most popular contemporary health approaches practiced by young adults in the United States. It is an ancient mind and body practice with origins in Indian philosophy dating to over 5,000 years ago. Yoga combines physical postures, rhythmic breathing, and meditative exercises to offer the participants a unique, holistic mind-body experience. In this report, the Sutras first introduced by Patanjali, an ancient Indian sage, are broken down into modern definitions. Each sutra has its own unique mental and physical benefits that can be attained by college students. Yama encourages maintaining a personal moral code. Niyama allows for personal connection and self-awareness. Asana refers to the poses that are still commonly practiced today. Pranayama helps to practice deep breathing. Pratyahara offers a disconnect from the world around us. Dharana allows us to focus and hone in on one thought. Dyana promotes a continuous flow of focus in meditation. Samadhi is reaching a state of pure relaxation. All of these take time and practice, but when implemented in different aspects of daily life, college students can reduce their overall stress and anxiety to improve focus and success.
ContributorsCarlson, Sophie (Author) / Penkrot, Tonya (Thesis director) / Lisenbee, Cayle (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2020-12
Description
The purpose of this study was to determine the impact of yoga intensity on stress in a population of college-aged females. Stress has been shown to negatively impact health both physically and mentally, therefore it is imperative that there is a way to combat these negative health effects. Participants included females between the ages of 18-25 who had been participating in physical activity 3-5 days per week (n=11). The subjects participated in two sessions of yoga, one of lower intensity, Hatha, and one of higher intensity, Vinyasa. Stress was measured by a Stress Indicators Questionnaire, which was modified to fit the aim of the study. It was filled out by the subjects pre and post each session, resulting in four questionnaires per subject. The yoga classes were displayed through a program called YogaGlo. The data was scored and analyzed with a modified scoring guideline based off of the questionnaire guidelines and with the use of Excel. The results showed that there was a statistically significant effect of both low (p value= 0.02) and high (p value= 0.01) intensity yoga on stress. There was not a statistically significant effect between the different yoga intensities on stress (p value= 0.3). Limitations of our study include a self-selective population, no control group, and demand characteristics. The results from this study should be used for further research on yoga and various aspects of mental health, such as anxiety and depression, with a female population of all ages, longer yoga sessions, and a longitudinal study format.
ContributorsSydenham, Isabella Anne (Co-author) / Edwards, Christina (Co-author) / Hoffner, Kristin (Thesis director) / Nolan, Nicole Blaize (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Objective: The purpose of the present study was to compare cardiovascular responses of two different types of yoga (Vinyasa Flow and Meditative).
Methods: 9 female college students (age 18-24) were assigned to two yoga sessions, Vinyasa Flow and Meditative yoga. Each participant attended one session of each type of yoga, where their cardiovascular responses were measured both pre and post yoga session. Heart rate, Rate of Perceived Exertion (RPE), and blood pressure were all measured.
Results: Meditative yoga showed a significant difference in the acute response of systolic blood pressure, diastolic blood pressure, and RPE. Vinyasa Flow yoga showed a significant difference the acute response of systolic blood pressure, diastolic blood pressure, and RPE. Heart rate was significantly different when comparing measurements before each yoga session. Systolic blood pressure, diastolic blood pressure, heart rate, and RPE were all significantly different when comparing acute measurements after each respective session. Significance was set to p < 0.05.
Conclusions: Overall, the hypothesis was supported that there was a difference in cardiovascular measurements. Meditative yoga was better at significantly decreasing blood pressure acutely, whereas Vinyasa Flow yoga increased blood pressure acutely. This suggests that Meditative yoga could be suggested over Vinyasa Flow yoga for certain individuals with hypertension. Differences between the yoga practices were found and the cardiovascular effects of different yoga practices can be better understood due to this research.
Methods: 9 female college students (age 18-24) were assigned to two yoga sessions, Vinyasa Flow and Meditative yoga. Each participant attended one session of each type of yoga, where their cardiovascular responses were measured both pre and post yoga session. Heart rate, Rate of Perceived Exertion (RPE), and blood pressure were all measured.
Results: Meditative yoga showed a significant difference in the acute response of systolic blood pressure, diastolic blood pressure, and RPE. Vinyasa Flow yoga showed a significant difference the acute response of systolic blood pressure, diastolic blood pressure, and RPE. Heart rate was significantly different when comparing measurements before each yoga session. Systolic blood pressure, diastolic blood pressure, heart rate, and RPE were all significantly different when comparing acute measurements after each respective session. Significance was set to p < 0.05.
Conclusions: Overall, the hypothesis was supported that there was a difference in cardiovascular measurements. Meditative yoga was better at significantly decreasing blood pressure acutely, whereas Vinyasa Flow yoga increased blood pressure acutely. This suggests that Meditative yoga could be suggested over Vinyasa Flow yoga for certain individuals with hypertension. Differences between the yoga practices were found and the cardiovascular effects of different yoga practices can be better understood due to this research.
ContributorsOberg, Martha Ann (Co-author) / Wood, Emilee (Co-author) / Nolan, Nicole (Thesis director) / Hoffner, Kristin (Committee member) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Purpose: The purpose of this study was to determine the efficacy of a yoga intervention for adolescents suffering from depression. Secondary results regarding the viability of yoga as an intervention for increasing self-esteem and decreasing anxiety were also explored.
Methods: Using PubMed, Medline, and CINAHL the search terms adolescents, depression, and yoga were searched for related articles. Articles were then excluded or included based on certain criteria. Focus was placed on articles written within the last 10 years as well as studies done on children within 10-19 years of age. Final articles underwent extraction for relevant information and comparisons were drawn between the studies.
Results: Final exclusion lead to a total of 5 suitable studies. Studies varied in styles of yoga performed and measurement scales used to assess depression. Populations of adolescents varied significantly as well. The majority of these studies showed significant improvement in depression symptoms when measuring from pre to post intervention. Similar improvements were also noted in anxiety symptoms and low self-esteem.
Conclusion: Data gathered indicated that yoga serves a suitable intervention for decreasing depression symptoms in adolescents. Additionally, there seems to be promising results regarding the viability of yoga as an intervention for decreasing symptoms of anxiety and increasing self-esteem. Despite, current promising results, there is need for more research to affirm the findings found in these articles to determine the long term effects of yoga interventions.
Methods: Using PubMed, Medline, and CINAHL the search terms adolescents, depression, and yoga were searched for related articles. Articles were then excluded or included based on certain criteria. Focus was placed on articles written within the last 10 years as well as studies done on children within 10-19 years of age. Final articles underwent extraction for relevant information and comparisons were drawn between the studies.
Results: Final exclusion lead to a total of 5 suitable studies. Studies varied in styles of yoga performed and measurement scales used to assess depression. Populations of adolescents varied significantly as well. The majority of these studies showed significant improvement in depression symptoms when measuring from pre to post intervention. Similar improvements were also noted in anxiety symptoms and low self-esteem.
Conclusion: Data gathered indicated that yoga serves a suitable intervention for decreasing depression symptoms in adolescents. Additionally, there seems to be promising results regarding the viability of yoga as an intervention for decreasing symptoms of anxiety and increasing self-esteem. Despite, current promising results, there is need for more research to affirm the findings found in these articles to determine the long term effects of yoga interventions.
ContributorsMenon, Pranav (Co-author) / Giedraitis, Frances (Co-author) / Larkey, Linda (Thesis director) / Calvin, Samantha (Committee member) / W.P. Carey School of Business (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
This is the study of Acute Impact of Ujjayi Yogic Pranayama vs Aerobic Exercise on Cognitive Performance and Short Term Memory. The purpose of this research was to compare two forms of exercise and their effects on someone's cognitive performance and short term memory. The research was performed in an acute setting were both exercises was conducted in under 15 minutes of active participation. The research question was; will aerobic exercise or the Pranayama breathing exercise provide better results and demonstrate a more effective way to increase the cognitive performance and short term memory for a college student aged 18-30. This was accomplished by using an aerobic exercise on an elliptical machine and then participating in the breathing exercise for 10 minutes in both scenarios. This study had two scenarios. Each scenario had a preliminary cognitive performance and short-term memory, post-Ujjayi exercise had a cognitive performance and short-term memory and a post-aerobic exercise had a cognitive performance and short-term memory. There was an hour break between Ujjayi exercise and aerobic exercise in both scenarios to prevent any type of bias. Scenario 1 had these three settings but the students were not given a breakfast supplement. In Scenario 2 the students were given a break supplement and followed the same procedures as scenario 1. There were 25 students for scenario 1 and 25 students for scenario 2. The students were allowed to participate in scenario 1 and 2 but it had to be a week after their first participation. All participants were originally signed up for scenario 1 and they could come back to perform scenario 2 a week later. The first scenario was completing the tests in the absence of food. Scenario two was completing the tests after having been given a Clif Bar to consume. The results of both of these scenarios showed that for cognitive performance and short term memory aerobic exercise had a beneficial impact on their performance. However, students who had a breakfast performed better on the preliminary tests and scored better after the yogic Ujjayi Pranayama exercise on their cognitive performance and short term memory tests. There was also a negligible difference between the test results after the preliminary tests and yogic Ujjayi Pranayama. However, in scenario one the overall tests scores for preliminary and yogic Ujjayi Pranayama were less than those in scenario two. Students who recorded that they were more actively engaging in regular physical exercise 3-7 days a week also did worse in scenario 1, but when presented with scenario 2 they scored equal with those who did not perform regular exercise. The overall purpose for this research was to find out how to increase cognitive performance and short term memory ability in college age students 18-30 in a short amount of time. The results of this study will be impactful for the future studies that will be focused on when comparing aerobic exercise and yogic pranayama.
ContributorsKopecky, Zachary (Co-author) / Enright, Roan (Co-author) / McILwraith, Heide (Thesis director) / Lee, Rebecca (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2017-05
Description
Abstract Objective: The purpose of this study was to determine the feasibility (e.g., practicality and demand) of a 4-week series of yoga classes in a homeless shelter. Participants: Five current residents of Central Arizona Shelter Services (CASS) and the Chief of Programming at CASS. Methods: Each shelter resident participated in a 5-minute interview answering questions regarding the demand of implementing a yoga program at CASS. The Chief of Programming participated in a 30-minute interview answering questions regarding the practicality of implementing a 4-week series yoga program at the homeless shelter. Results: CASS residents reported a strong desire to attend a yoga program. The Chief of Programming at CASS reported that implementing a yoga program would conflict with the overall goal of the shelter. Conclusion: Implementing a 4-week series yoga program is not feasible at CASS although there is a strong demand for a yoga program among the homeless population of the Phoenix metro area.
ContributorsSamuels, Jasmyne Angelique (Author) / Hart, Teresa (Thesis director) / Huberty, Jennifer (Committee member) / Pearl, Julia (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
Recent research has confirmed and revealed many physical and mental benefits of yoga. The practice of yoga has spread throughout the western world, where it is widely used for the purpose of exercise and fitness. Due to its rise in popularity, there is a need for research regarding the energy expenditure required for different types of yoga. The majority of the literature cites yoga as being an effective exercise for light intensity activity, but there are not as many studies attempting to determine if there are postures and sequences that can meet the requirements for moderate physical activity. In addition, there is a need to validate mobile devices with which to measure energy expenditure (EE) that are compatible with the dynamic movements that occur during yoga. The purpose of this study was to measure energy expenditure of twenty-two yoga practitioners of varying experience during a 30-minute Vinyasa flow yoga practice and from this data collection determine: if an ashtanga-based vinyasa yoga class meets the criteria for moderate intensity physical activity, the reliability between the Actigraph and Oxycon Mobile and the validity of an Actigraph GT3X device worn on the hip in estimating energy expenditure for ashtanga-based vinyasa flow yoga. The Actigraph GT3X and the Oxycon mobile were used to measure energy expenditure. Mean values for energy expenditure recorded by the Oxycon and Actigraph were 3.19 ± 0.42 METs and 1.16 ± 0.23 METs respectively, exhibiting a significant difference in data collection. There was no correlation between the values recorded by the two devices, indicating that the Actigraph was not consistent with the Oxycon Mobile (previously validated for measurement of EE). Results of this study indicate that this Vinyasa flow yoga sequence does satisfy the criteria for moderate intensity physical activity as defined by ACSM with an average EE of 3.19 ± 0.42 METs, and that the Actigraph GT3X is not an accurate device for measurement of EE for yoga.
ContributorsHand, Lindsay Gabrielle (Author) / Huberty, Jennifer (Thesis director) / Buman, Matthew (Committee member) / School of Nutrition and Health Promotion (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
This purpose of this thesis study was to examine variables of the "War on Cancer" frame, loss-gain prime, and patient gender on treatment decision for advanced cancer patients. A total of 291 participants (141 females) participated in an online survey experiment and were randomly assigned to one of eight possible conditions, each of which were comprised of a combination of one of two levels for three total independent variables: war frame ("War on Cancer" frame or neutral frame), loss-gain prime (loss prime or gain prime), and patient gender (female or male). Each of the three variables were operationalized to determine whether or not the exposure to the war on cancer paradigm, loss-frame language, or male patient gender would increase the likelihood of a participant choosing a more aggressive cancer treatment. Participants read a patient scenario and were asked to respond to questions related to motivating factors. Participants were then asked to report preference for one of two treatment decisions. Participants were then asked to provide brief demographic information in addition to responding to questions about military history, war attitudes, and cancer history. The aforementioned manipulations sought to determine whether exposure to various factors would make a substantive difference in final treatment decision. Contrary to the predicted results, participants in the war frame condition (M = 3.85, SD = 1.48) were more likely to choose the pursuit of palliative care (as opposed to aggressive treatment) than participants in the neutral frame condition (M = 3.54, SD = 1.23). Ultimately, these significant findings suggest that there is practical information to be gained from treatment presentation manipulations. By arming healthcare providers with a more pointed understanding of the nuances of treatment presentation, we can hope to empower patients, their loved ones, and healthcare providers entrenched in the world of cancer treatment.
ContributorsKnowles, Madelyn Ann (Author) / Kwan, Virginia S. Y. (Thesis director) / Presson, Clark (Committee member) / Salamone, Damien (Committee member) / Department of Psychology (Contributor) / School of Human Evolution and Social Change (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05