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This dissertation centers on the development of Bayesian methods for learning differ- ent types of variation in switching nonlinear gene regulatory networks (GRNs). A new nonlinear and dynamic multivariate GRN model is introduced to account for different sources of variability in GRNs. The new model is aimed at more precisely

This dissertation centers on the development of Bayesian methods for learning differ- ent types of variation in switching nonlinear gene regulatory networks (GRNs). A new nonlinear and dynamic multivariate GRN model is introduced to account for different sources of variability in GRNs. The new model is aimed at more precisely capturing the complexity of GRN interactions through the introduction of time-varying kinetic order parameters, while allowing for variability in multiple model parameters. This model is used as the drift function in the development of several stochastic GRN mod- els based on Langevin dynamics. Six models are introduced which capture intrinsic and extrinsic noise in GRNs, thereby providing a full characterization of a stochastic regulatory system. A Bayesian hierarchical approach is developed for learning the Langevin model which best describes the noise dynamics at each time step. The trajectory of the state, which are the gene expression values, as well as the indicator corresponding to the correct noise model are estimated via sequential Monte Carlo (SMC) with a high degree of accuracy. To address the problem of time-varying regulatory interactions, a Bayesian hierarchical model is introduced for learning variation in switching GRN architectures with unknown measurement noise covariance. The trajectory of the state and the indicator corresponding to the network configuration at each time point are estimated using SMC. This work is extended to a fully Bayesian hierarchical model to account for uncertainty in the process noise covariance associated with each network architecture. An SMC algorithm with local Gibbs sampling is developed to estimate the trajectory of the state and the indicator correspond- ing to the network configuration at each time point with a high degree of accuracy. The results demonstrate the efficacy of Bayesian methods for learning information in switching nonlinear GRNs.
ContributorsVélez-Cruz, Nayely (Author) / Papandreou-Suppappola, Antonia (Thesis advisor) / Moraffah, Bahman (Committee member) / Tepedelenlioğlu, Cihan (Committee member) / Berisha, Visar (Committee member) / Arizona State University (Publisher)
Created2023
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Description
The present outlook in power systems is rapidly changing due to the introduction of (1) new active devices into the grid, such as photovoltaic (PV) panels, wind generators, and energy storage devices, and (2) new data from sensing and control devices. While this abundant data improves situational awareness and enhances

The present outlook in power systems is rapidly changing due to the introduction of (1) new active devices into the grid, such as photovoltaic (PV) panels, wind generators, and energy storage devices, and (2) new data from sensing and control devices. While this abundant data improves situational awareness and enhances control schemes, it can make the power grid more vulnerable than ever to cyber-attacks with dire consequences. Cyberattack withdraws much attention due to its potential impact, its financial losses, and its implications for national security. To understand the risks, this work looks into the operation of the electric grids, e.g., how to solve power flow equations. Specifically, this work investigates the good and the bad parts of existing methods and proposes to have a stochastic solution for power flow analysis for robustness. The finding is that no matter how the solution method is improved, system information is crucial to securely analyzing the grid. This gives utilities a false sense of security by hiding such information. For example, in a false data injection attack (FDIA), an attacker must know system information and measurements. If system information is hidden, the grid seems impossible to attack successfully, e.g., passing the Chi-square test based on system information. This dissertation shows that a carefully designed system can not only attack successfully but also with a strong performance guarantee.
ContributorsCostilla-Enriquez, Napoleon (Author) / Weng, Yang YG (Thesis advisor) / Arizona State University (Publisher)
Created2023
Description
Engineering, and more specifically, electrical engineering can be a difficult topic to explain through spoken communication. Along with taking years of education to learn and understand necessary topics, the field is riddled with jargon and items that may take lectures to explain. However, this type of education may not be

Engineering, and more specifically, electrical engineering can be a difficult topic to explain through spoken communication. Along with taking years of education to learn and understand necessary topics, the field is riddled with jargon and items that may take lectures to explain. However, this type of education may not be feasible for a younger or inexperienced audience. Therefore, engineers must find new ways to explain such difficult topics, especially in an attempt to garner interest in children, for example, through art.
ContributorsHedges, Madison (Author) / Aukes, Daniel (Thesis director) / Weeks, Eric (Committee member) / Barrett, The Honors College (Contributor) / Engineering Programs (Contributor) / School of Earth and Space Exploration (Contributor)
Created2023-12
Description
This research explores the potential use of microwave energy to detect various substances in water, with a focus on water quality assessment and pathogen detection applications. There are many non-thermal effects of microwaves on microorganisms and their resonant frequencies could be used to identify and possibly destroy harmful pathogens, such

This research explores the potential use of microwave energy to detect various substances in water, with a focus on water quality assessment and pathogen detection applications. There are many non-thermal effects of microwaves on microorganisms and their resonant frequencies could be used to identify and possibly destroy harmful pathogens, such as bacteria and viruses, without heating the water. A wide range of materials, including living organisms like Daphnia and Moina, plants, sand, plastic, and salt, were subjected to microwave measurements to assess their influence on the transmission (S21) measurements. The measurements of the living organisms did not display distinctive resonant frequencies and variations in water volume may be the source of the small measurement differences. Conversely, sand and plastic pellets affected the measurements differently, with their arrangement within the test tube emerging as a significant factor. This study also explores the impact of salinity on measurements, revealing a clear pattern that can be modeled as a series RLC resonator. Although unique resonant frequencies for the tested organisms were not identified, the presented system demonstrates the potential for detecting contaminants based on variations in measurements. Future research may extend this work to include a broader array of organisms and enhance measurement precision.
ContributorsChild, Carson (Author) / Aberle, James (Thesis director) / Blain Christen, Jennifer (Committee member) / Barrett, The Honors College (Contributor) / Electrical Engineering Program (Contributor)
Created2023-12
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Description
Digital signal processing accelerator architectures are designed to provide either high-energy efficiency or high programmability depending on the targeted application and use case. For example, Domain Adaptive Processor (DAP), a highly reconfigurable array architecture, designed by University of Michigan, for signal processing workloads is highly energy efficient but difficult to

Digital signal processing accelerator architectures are designed to provide either high-energy efficiency or high programmability depending on the targeted application and use case. For example, Domain Adaptive Processor (DAP), a highly reconfigurable array architecture, designed by University of Michigan, for signal processing workloads is highly energy efficient but difficult to program. DAP consists of 8x8 array of Processing elements (PE) with each PE containing four heterogeneous SUB-PEs. Each SUB-PE has its own instruction memory and is capable of executing Very Large Instruction Word (VLIW) instructions. Unfortunately, instructions have to be written for every cycle of computation for each SUB-PE used in the application and handcrafted such that all the inter-PE dependencies are synchronized. This thesis builds up on prior work at Arizona State University(ASU) to make DAP more programmable. First, the compiler back-end developed at ASU is extended with more features. Prior work introduced DAP Instruction Set Architecture (ISA), an assembly instruction format, and proposed a compiler framework, called DAP Assembler, with optimization passes to reduce the complexity of programming applications in DAP. While this back-end infrastructure helped generated code with relative ease compared to Very Large Instruction Word (VLIW) code by hand, the output of the code generated was not software-pipelined and the code generated for each Processing Element(PE) had to be manually synchronized. So in this thesis, DAP Assembler tool is extended to support software-pipelining for high throughput applications. Further, a generic synchronization tool is proposed to synchronize instructions in a multi-PE setup and integrated with DAP Assembler to generate synchronized high-throughput application code. Second, a Multi-Level Intermediate Representation(MLIR) based compiler front-end infrastructure is proposed to first lower the application code written by the programmer to an Intermediate Representation (IR) that is suitable for generic array architectures and then further converted to DAP-specific IR that can be used for generating machine code for DAP using DAP ISA. This two stage process enables this infrastructure to be more easily adapted to other array architectures. The first conversion pass uses a designer-provided modular hardware architecture information, called Resource Registry, to allocate operations in the input IR to resources in the Resource registry and capture all data movement. While the resource registry changes from architecture to architecture, the conversion pass algorithm is generic and can be used for other architectures. The second conversion pass is more geared towards DAP and integrates DAP specific constructs to generate optimized instruction in DAP ISA. Multiple kernels such as matrix multiplication, vector-vector addition were implemented using this infrastructure and the code generated by the tool verified to be functionally correct.
ContributorsMurugan, Narayanan (Author) / Chakrabarti, Chaitali Dr (Thesis advisor) / Akoglu, Ali Dr (Committee member) / Bliss, Daniel Dr (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Kuwait is committed to implementing the Kyoto Protocol in “Vision 2035” to reduce greenhouse gas emissions by shifting to the use of wind and solar energies [1]. The specific goal of the Vision 2035 is for renewables to comprise 15% of Kuwait’s electrical generation by 2030. Wind and solar are

Kuwait is committed to implementing the Kyoto Protocol in “Vision 2035” to reduce greenhouse gas emissions by shifting to the use of wind and solar energies [1]. The specific goal of the Vision 2035 is for renewables to comprise 15% of Kuwait’s electrical generation by 2030. Wind and solar are abundant in Kuwait and can easily provide 15% of the total electrical generation. However, there are three significant obstacles. The first is Kuwait currently depends heavily on rapidly diminishing fossil fuels which are the major sources of CO2, NOx, and SOx emissions. Unfortunately, current plans are to build two conventional power stations by 2024. The purpose is to cover the energy needs for growing population. The second problem is that Kuwait has a very small land area. Consequently, there is limited space to build new utility-scale renewable power stations. The third issue is the low electricity tariff provides little incentive for the population to save energy. Offshore wind farms have the potential to provide thousands of GWh/yr to accomplish the goals of Vision 2035. Kuwait has a vast untapped supply of offshore wind energy. Specifically, there are eight offshore locations in which 50 turbines could be built each, for a total of 400 turbines. Using 4.2 MW turbines, this would provide 1.68 GW of wind energy, and increase the renewable portion of the electrical energy production to 13.93% (including Shagaya renewable park). Installing battery storage with the proposed wind turbines could provide fast ramp response which would serve to complement existing power production on Kuwait’s grid. In this work, six different turbines with different sizes are considered from 2.5 MW to 4.2 MW (from well-known manufacturers, such as, Nordex and Vestas), but ultimately 4.2 MW turbines are recommended. Data for this study has been supplied by: A) Civil Aviation -- temperature and wind speed, B) Ministry of Electricity and Water (MEW) -- electricity data, and C) Public Authority for Civil Information -- population data.
ContributorsAlotaibi, Abdullah Saqer (Author) / Calhoun, Ronald (Thesis advisor) / Kitchen, Jennifer (Thesis advisor) / Roedel, Ronald (Committee member) / Mayyas, Abdul Ra'ouf (Committee member) / Arizona State University (Publisher)
Created2020
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Description
In this dissertation, I investigate the electronic properties of two important silicon(Si)-based heterojunctions 1) hydrogenated amorphous silicon/crystalline silicon (a-Si:H/c-Si) which has already been commercialized in Heterojunction with Intrinsic Thin-layer (HIT) cells and 2) gallium phosphide/silicon (GaP/Si) which has been suggested to be a good candidate for replacing a-Si:H/c-Si in HIT

In this dissertation, I investigate the electronic properties of two important silicon(Si)-based heterojunctions 1) hydrogenated amorphous silicon/crystalline silicon (a-Si:H/c-Si) which has already been commercialized in Heterojunction with Intrinsic Thin-layer (HIT) cells and 2) gallium phosphide/silicon (GaP/Si) which has been suggested to be a good candidate for replacing a-Si:H/c-Si in HIT cells in order to boost the HIT cell’s efficiency.

In the first part, the defect states of amorphous silicon (a-Si) and a-Si:H material are studied using density functional theory (DFT). I first employ simulated annealing using molecular dynamics (MD) to create stable configurations of a-Si:H, and then analyze the atomic and electronic structure to investigate which structural defects interact with H, and how the electronic structure changes with H addition. I find that H atoms decrease the density of mid-gap states and increase the band gap of a-Si by binding to Si atoms with strained bonds. My results also indicate that Si atoms with strained bonds creates high-localized orbitals in the mobility gap of a-Si, and the binding of H atoms to them can dramatically decrease their degree of localization.



In the second part, I explore the effect of the H binding configuration on the electronic properties of a-Si:H/c-Si heterostructure using density functional theory studies of models of the interface between a-Si:H and c-Si. The electronic properties from DFT show that depending on the energy difference between configurations, the electronic properties are sensitive to the H binding configurations.

In the last part, I examine the electronic structure of GaP/Si(001) heterojunctions and the effect of hydrogen H passivation at the interface in comparison to interface mixing, through DFT calculations. My calculations show that due to the heterovalent mismatch nature of the GaP/Si interface, there is a high density of localized states at the abrupt GaP/Si interface due to the excess charge associated with heterovalent bonding, as reported elsewhere. I find that the addition of H leads to additional bonding at the interface which mitigates the charge imbalance, and greatly reduces the density of localized states, leading to a nearly ideal heterojunction.
ContributorsVatan Meidanshahi, Reza (Author) / Goodnick, Stephen Marshall (Thesis advisor) / Vasileska, Dragica (Committee member) / Bowden, Stuart (Committee member) / Honsberg, Christiana (Committee member) / Arizona State University (Publisher)
Created2019
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Description
Over the past few years, research into the use of doped diamond in electronics has seen an exponential growth. In the course of finding ways to reduce the contact resistivity, nanocarbon materials have been an interesting focus. In this work, the transfer length method (TLM) was used to investigate Ohmic

Over the past few years, research into the use of doped diamond in electronics has seen an exponential growth. In the course of finding ways to reduce the contact resistivity, nanocarbon materials have been an interesting focus. In this work, the transfer length method (TLM) was used to investigate Ohmic contact properties using the tri-layer stack Ti/Pt/Au on nitrogen-doped n-type conducting nano-carbon (nanoC) layers grown on (100) diamond substrates. The nanocarbon material was characterized using Secondary Ion Mass Spectrometry (SIMS), Scanning electron Microscopy (SEM) X-ray diffraction (XRD), Raman scattering and Hall effect measurements to probe the materials characteristics. Room temperature electrical measurements were taken, and samples were annealed to observe changes in electrical conductivity. Low specific contact resistivity values of 8 x 10^-5 Ωcm^2 were achieved, which was almost two orders of magnitude lower than previously reported values. The results were attributed to the increased nitrogen incorporation, and the presence of electrically active defects which leads to an increase in conduction in the nanocarbon. Further a study of light phosphorus doped layers using similar methods with Ti/Pt/Au contacts again yielded a low contact resistivity of about 9.88 x 10^-2 Ωcm^2 which is an interesting prospect among lightly doped diamond films for applications in devices such as transistors. In addition, for the first time, hafnium was substituted for Ti in the contact stack (Hf/Pt/Au) and studied on nitrogen doped nanocarbon films, which resulted in low contact resistivity values on the order of 10^-2 Ωcm^2. The implications of the results were discussed, and recommendations for improving the experimental process was outlined. Lastly, a method for the selective area growth of nanocarbon was developed and studied and the results provided an insight into how different characterizations can be used to confirm the presence of the nanocrystalline diamond material, the limitations due to the film thickness was explored and ideas for future work was proposed.
ContributorsAmonoo, Evangeline Abena (Author) / Thornton, Trevor (Thesis advisor) / Alford, Terry L (Thesis advisor) / Anwar, Shahriar (Committee member) / Theodore, David (Committee member) / Arizona State University (Publisher)
Created2023
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Description
Scaling of the Metal-Oxide-Semiconductor Field Effect Transistor (MOSFET) towards shorter channel lengths, has lead to an increasing importance of quantum effects on the device performance. Until now, a semi-classical model based on Monte Carlo method for instance, has been sufficient to address these issues in silicon, and arrive at a

Scaling of the Metal-Oxide-Semiconductor Field Effect Transistor (MOSFET) towards shorter channel lengths, has lead to an increasing importance of quantum effects on the device performance. Until now, a semi-classical model based on Monte Carlo method for instance, has been sufficient to address these issues in silicon, and arrive at a reasonably good fit to experimental mobility data. But as the semiconductor world moves towards 10nm technology, many of the basic assumptions in this method, namely the very fundamental Fermi’s golden rule come into question. The derivation of the Fermi’s golden rule assumes that the scattering is infrequent (therefore the long time limit) and the collision duration time is zero. This thesis overcomes some of the limitations of the above approach by successfully developing a quantum mechanical simulator that can model the low-field inversion layer mobility in silicon MOS capacitors and other inversion layers as well. It solves for the scattering induced collisional broadening of the states by accounting for the various scattering mechanisms present in silicon through the non-equilibrium based near-equilibrium Green’s Functions approach, which shall be referred to as near-equilibrium Green’s Function (nEGF) in this work. It adopts a two-loop approach, where the outer loop solves for the self-consistency between the potential and the subband sheet charge density by solving the Poisson and the Schrödinger equations self-consistently. The inner loop solves for the nEGF (renormalization of the spectrum and the broadening of the states), self-consistently using the self-consistent Born approximation, which is then used to compute the mobility using the Green-Kubo Formalism.
ContributorsJayaram Thulasingam, Gokula Kannan (Author) / Vasileska, Dragica (Thesis advisor) / Ferry, David (Committee member) / Goodnick, Stephen (Committee member) / Allee, David (Committee member) / Arizona State University (Publisher)
Created2017
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Description
An efficient thermal solver is available in the CMC that allows modeling self-heating in the electrical simulations, which treats phonons as flux and solves the energy balance equation to quantify thermal effects. Using this solver, thermal simulations were performed on GaN-HEMTs in order to test effect of gate architectures on

An efficient thermal solver is available in the CMC that allows modeling self-heating in the electrical simulations, which treats phonons as flux and solves the energy balance equation to quantify thermal effects. Using this solver, thermal simulations were performed on GaN-HEMTs in order to test effect of gate architectures on the DC and RF performance of the device. A Π- gate geometry is found to suppress 19.75% more hot electrons corresponding to a DC power of 2.493 W/mm for Vgs = -0.6V (max transconductance) with respect to the initial T-gate. For the DC performance, the output current, Ids is nearly same for each device configuration over the entire bias range. For the RF performance, the current gain was evaluated over a frequency range 20 GHz to 120 GHz in each device for both thermal (including self-heating) and isothermal (without self-heating). The evaluated cutoff frequency is around 7% lower for the thermal case than the isothermal case. The simulated cutoff frequency closely follows the experimental cutoff frequency. The work was extended to the study of ultra-wide bandgap material (Diamond), where isotope effect causes major deterioration in thermal conductivity. In this case, bulk phonons are modeled as semiclassical particles solving the nonlinear Peierls - Boltzmann transport equation with a stochastic approach. Simulations were performed for 0.001% (ultra-pure), 0.1% and 1.07% isotope concentration (13C) of diamond, showing good agreement with the experimental values. Further investigation was performed on the effect of isotope on the dynamics of individual phonon branches, thermal conductivity and the mean free path, to identify the dominant phonon branch. Acoustic phonons are found to be the principal contributors to thermal conductivity across all isotope concentrations with transverse acoustic (TA2) branch is the dominant branch with a contribution of 40% at room temperature and 37% at 500K. Mean free path computations show the lower bound of device dimensions in order to obtain maximum thermal conductivity. At 300K, the lowest mean free path (which is attributed to Longitudinal Optical phonon) reduces from 24nm to 8 nm for isotope concentration of 0.001% and 1.07% respectively. Similarly, the maximum mean free path (which is attributed to Longitudinal Acoustic phonon) reduces from 4 µm to 3.1 µm, respectively, for the same isotope concentrations. Furthermore, PETSc (Portable, Extensible Toolkit for Scientific Computation) developed by Argonne National Lab, was included in the existing Cellular Monte Carlo device simulator as a Poisson solver to further extend the capability of the simulator. The validity of the solver was tested performing 2D and 3D simulations and the results were compared with the well-established multigrid Poisson solver.
ContributorsAcharjee, Joy (Author) / Saraniti, Marco (Thesis advisor) / Goodnick, Stephen (Committee member) / Thornton, Trevor (Committee member) / Wang, Robert (Committee member) / Arizona State University (Publisher)
Created2024