Matching Items (13)
Filtering by
- All Subjects: Education
- All Subjects: conservation
Description
White-nose syndrome (WNS) is a fungal infection devastating bat populations throughout eastern North America. WNS is caused by a fungus, Pseudogymnoascus destructans (Pd), that invades the skin of hibernating bats. While there are a number of treatments being researched, there is currently no effective treatment for WNS that is deployed in the field, except a few being tested on a limited scale. Bats have lowered immune function and response during hibernation, which may increase susceptibility to infection during the winter months. Antimicrobial peptides (AMPs) are a crucial component of the innate immune system and serve as barriers against infection. AMPs are constitutively expressed on skin and facilitate wound healing, stimulate other immune responses, and may also stay active on bat skin during hibernation. AMPs are expressed by all tissues, have direct killing abilities against microbes, and are a potential treatment for bats infected with Pd. In this investigation, the fungicidal activity of several readily available commercial AMPs were compared, and killing assay protocols previously investigated by Frasier and Lake were replicated to establish a control trial for use in future killing assays. Another aim of this investigation was to synthesize a bat-derived AMP for use in the killing assay. Sequences of bat-derived AMPs have been identified in bat skin samples obtained from a large geographic sampling of susceptible and resistant species. Contact was made with GenScript Inc., the company from which commercially available AMPs were purchased, to determine the characteristics of peptide sequences needed to synthesize an AMP for lab use. Based on recommendations from GenScript Inc., peptide sequences need to have a hydrophobicity of less than 50% and a sequence length of less than 50 amino acids. These criteria serve as a potential barrier because none of the known bat-derived sequences analyzed satisfy both of these requirements. The final aim of this study was to generate a conceptual model of the immune response molecules activated when bats are exposed to a fungal pathogen such as Pd. Overall, this work investigated sources of variability between trials of the killing assay, analyzed known bat-derived peptide sequences, and generated a conceptual model that will serve as a guideline for identification of immune response molecules on the skin of bats in future proteomics work.
ContributorsBarton, Madisen L (Author) / Moore, Marianne (Thesis director) / Penton, Christopher (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
Conservation is a complicated entity consisting of a multitude of professional fields including social issues, cultural issues, and physical science. This thesis evaluates the positive and negative aspects of two broad types of conservation: top down fortress conservation and bottom up community-based conservation. Fortress conservation has many negative aspects, such as displacing human communities and preventing utilization of resources. However, it also has positive aspects, such as preventing the destruction of delicate ecosystems and slowing down extinctions. Community-based conservation is more inclusive and focuses on including the indigenous populations located within the proposed conservation site in the decision-making process. Its negatives include having an anthropocentric goal instead of valuing nature's intrinsic values. Understanding the differences inherent in these two methods is necessary in order to implement a conservation network with the highest chance for success.
ContributorsFink, Laurel Berylline (Author) / Smith, Andrew (Thesis director) / Collins, James (Committee member) / Minteer, Ben (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2014-05
Description
Nutrition has been around for as long as human beings have resided on the planet, giving it one of the most impactful roles in history, particularly in medicine. Certain herbs or dietary restrictions could help individuals recover from illnesses—this form of healing has been passed down generations, which medical providers from all over the world take advantage of. Before the era of antibiotics and pharmaceutical companies, food was the medicine used to treat. As civilization has flourished and become progressive, it seems that certain qualities of the past have been forgotten, such as the power of diet. Medical providers like to push patients towards pharmaceutical intervention because of the financial profit that this method entails, which has been shown to backfire. These interventions are not solving the true problem, but only applying a short-term solution. Dietary restrictions as well as the increase in heart-healthy foods can entirely reverse these conditions in order to avoid the fatal effects they may have. With the increase in nutritional education amongst the population via medical providers, specifically primary care providers, patients are able to reverse the symptoms of effects of chronic cardiovascular disease amongst others.
ContributorsTarin, Marjan (Author) / Huffman, Holly (Thesis director) / Moore, Marianne (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12
Description
Science and technology have significant influence over the everyday lives of ordinary citizens. As these two disciplines have become more advanced, their influence has only become more pronounced, leading to many socioscientific issues and bioethical dilemmas that society and scientists must grapple with. In order to create informed, thoughtful citizens and effective future scientists, science educators must provide students with the skills they need to assess, evaluate, and address bioethical controversies. To do this, educators must explicitly teach students about bioethics and scientific argumentation. However, currently, this content is not commonly taught in science classrooms. Instead, science is presented as a discipline in which there are clear answers. Students are often expected to memorize lists of facts and are not made aware of the impact that science has on their own lives and those of others. This three-lesson unit seeks to help students make the connections between science content and its social implications and teach them the scientific argumentation skills necessary to critically evaluate and defend their positions regarding bioethical dilemmas. In the first lesson, students learn about bioethics and practice developing potential solutions to hypothetical bioethical dilemmas. In the second lesson, students are introduced to scientific argumentation and use their new skills to create mini-arguments regarding the bioethics of what happened to Henrietta Lacks, a black woman whose cervical cancer cells were used in research without her consent. Finally, in the third lesson, students work in groups to create fully developed arguments that support their position regarding the issue of tissue ownership. The last two lessons of the unit were implemented in a high school science classroom. After implementation, it was found that students have strong opinions regarding scientific controversies and enjoy learning and arguing about the social implications of science. However, students struggled to understand the mechanics of scientific argumentation and had trouble clearly expressing their ideas and opinions via argumentation. Additionally, students were very dogmatic in their positions and displayed a lack of understanding of the nuance of bioethical controversies.
ContributorsNath, Anita Lakshmi (Author) / Walters, Molina (Thesis director) / Oliver, Jill (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
Description
The use of genetic management in conservation has sparked much debate around the ethical and environmental impacts of the plans. A case study on the conservation of leopard frogs in Arizona was analyzed to better understand the benefits and issues surrounding genetic management plans. The first part of the case focuses on the recent management plan for Chiricahua Leopard Frogs implemented by the Arizona Game and Fish Department. The goal of the plan is to better understand the genetic dynamics of the established Chiricahua Leopard Frog populations to develop a more effective management plan. The second part of the case focuses on the Arizona Game and Fish Department’s management of the Northern Leopard Frog. There was little success with the initial breed and release program of the native species, however a nonnative subspecies of Northern Leopard Frog was able to establish a thriving population. This case study exemplifies the many complications with genetic management plans and the importance of careful assessment of options when deciding on a genetic management plan. Despite the complexity of genetic management plans, it is an important method to consider when discussing the conservation of a species.
ContributorsTurpen, Alexa (Author) / Murphree, Julie (Thesis director) / Collins, James (Thesis director) / Owens, Audrey (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor) / College of Integrative Sciences and Arts (Contributor) / School of Mathematical and Natural Sciences (Contributor)
Created2024-05
Description
This research highlights how problems that women face at the structural, social, professional and individual level impact their business success, personal growth, and the business economic environment. The first section of the paper provides a global view about gender gaps and challenges. The second section is narrowed down to the city of Baños de Agua Santa in Ecuador where the findings were sought through a grounded theory research. After the analysis of the findings, a business model has been developed which addresses the major challenges and problems that women and the city are currently encountering. The ultimate purpose is to implement the project in the city; it promotes entrepreneurial education, innovation, association, and personal growth. The overall research is a cutting-edge study as it emphasizes that the business success of women entrepreneurs is not solved by one big fixed but more through a holistic solution.
ContributorsCurrat Luna, Daphne Christelle (Author) / Mary, Sully De Luque (Thesis director) / Joshua, Ault (Committee member) / Thunderbird School of Global Management (Contributor) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2019-12
Description
My thesis/creative project is a series of videos, supplemented by a paper documenting all the research. The project focuses on domestic and feral cats through the viewpoint of the “warrior cats” book series. The use of a particular fandom as a vehicle for science communication is a unique platform for use as a thesis/creative project. The narrated videos are made with the intention of being presented on YouTube or a similar viewing platform to an audience that is already familiar with the book series. The videos would fit on the site as a form of educational film known as video essays. The videos cover a range of topics to relate this book series to real situations with domestic animals, particularly cats, and wildlife. Each video is around ten to twenty minutes long and presented as episodes in a series.
The objective of my thesis project is to help bridge the gap between entertainment and science. I grew up reading the warrior cats, and I assume I was similar to many other children and young teens who did not understand domestic cats or ecology enough to question anything in the books. I know that much of these books are fictional, but that does not mean that it can’t be analyzed and used as a tool for teaching. The goal is to reach common ground with those people who have an interest in the warrior cats series, and help them understand it in a new light, as well as the world around them. I aim for the takeaway of this series to encourage people to explore the concepts I discuss and consider expanding upon the ideas within the Warriors universe or with their own cats.
The objective of my thesis project is to help bridge the gap between entertainment and science. I grew up reading the warrior cats, and I assume I was similar to many other children and young teens who did not understand domestic cats or ecology enough to question anything in the books. I know that much of these books are fictional, but that does not mean that it can’t be analyzed and used as a tool for teaching. The goal is to reach common ground with those people who have an interest in the warrior cats series, and help them understand it in a new light, as well as the world around them. I aim for the takeaway of this series to encourage people to explore the concepts I discuss and consider expanding upon the ideas within the Warriors universe or with their own cats.
ContributorsGarcia, Johnny Nico (Author) / Bateman, Heather (Thesis director) / Meloy, Elizabeth (Committee member) / College of Integrative Sciences and Arts (Contributor, Contributor) / School of Art (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
The Tale of the Tigers is a children’s picture book in which a tiger named Guava is transported from his world of Serenia to our world. In an attempt to find someone to help him with this situation, Guava meets another tiger named Papaya. After having his prey scared away by Guava, Papaya begins to explain the different hardships and dangers that tigers face in their natural habitat. Papaya also teaches Guava about the different programs and activities that humans have been doing to help increase and restore tiger populations. At the end of the story, Guava returns to his world and spreads awareness to those that live in Serenia about how tigers are threatened in other places and what’s being done to help them. Papaya uses basic ecological concepts to explain the importance of tigers in their ecosystem. These concepts include habitat loss, trophic levels, landscape fragmentation, and poaching. The story also incorporates different conservation methods, including captive breeding and the use of camera traps.
ContributorsMooney, Lena (Author) / Jesse, Lewis (Thesis director) / Meloy, Elizabeth (Committee member) / College of Integrative Sciences and Arts (Contributor, Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
There is little research on volunteer tourism to primate sanctuaries. The purpose of this study was to help fill this knowledge gap and gain insights into how animal sanctuaries with volunteers in Costa Rica can be improved operationally to strengthen their conservation efforts. My research questions were: 1. How does volunteer tourism with primates in Costa Rica affect volunteers? 2. How does this volunteer tourism affect Costa Rica’s environment? The methodology used was an exploratory qualitative design that included a literature review of previous research and case studies and a visit with interviews at a primate sanctuary in Costa Rica. The findings did not generate sufficient data to answer the first research question. I did find that altruism was a key factor in recruiting effective volunteers. The study also found that conservation in Costa Rica relies on volunteer tourism to fill a human resource gap. This research will allow sanctuaries in Costa Rica to respond better to protect biodiversity.
ContributorsCavalier, Rebecca (Author) / Chhetri, Nalini (Thesis director) / Castillo, Elizabeth (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2020-05
Description
Since the days of Plato’s Academy and Aristotle’s Lyceum, the intellectual community has been divided in two. This division has continued into the present day, most notably evidenced by the dichotomy between science and arts majors. There has been much debate over the last two centuries regarding how to bridge this divide, and whether or not doing so is necessary. Scholars like C. P. Snow have argued that interdisciplinary education is humanity’s only hope for confronting its current and future problems, while scholars like F.R. Leavis believe calls to restructure education are an oversimplification of a more complex problem. With its emphasis on global and local outreach, interdisciplinary education, and use-inspired research, the New American University model currently in use by Arizona State University is a literal attempt at bridging this divide. Schools like the College of Integrated Sciences and Arts have created an environment that encourages interdisciplinary collaboration. President Crow attributes this progress to what he calls “the design approach.” Unlike a rigid blueprint, the design approach instead looks at each problem in isolation, allowing for a unique solution to be tailor-made to fit each scenario. Despite the initial successes of the New American University model, however, it is still important to remain observant and critical of its practices into the future, as too much of an emphasis on interdisciplinarity could have the opposite of its intended effect, and potentially drive students who wish to specialize away from traditional universities altogether.
ContributorsPeru, James (Author) / Martin, Thomas (Thesis director) / Kane, Joshua (Committee member) / College of Integrative Sciences and Arts (Contributor) / Barrett, The Honors College (Contributor)
Created2018-12