Full metadata
Title
Characterization of Exosomes In Pediatric Cancer Cells
Description
Exosomes have been known to secrete an increased amount of miRNA and noncoding genes that are abnormally expressed in various cancer subtypes. Thus, they may be an early marker for pediatric cancer types that are more difficult to diagnosis without invasive techniques, and may also help identify progression of the disease. In the project, six types of pediatric cancer cell lines, along with their extracted exosomes, were analyzed and tested for different monoclonal antibodies through western blot analysis. The genes EWS-FLI1 and FGFR4 were also identified in some cancer cell lines through Reverse-Transcriptase Polymerase Chain Reaction analysis (RT-PCR). The results were indicative of similar protein markers being found in both the originating cells and their corresponding exosomes.
Date Created
2017-12
Contributors
- Kaur Bhinder, Harsimran (Author)
- Lake, Douglas (Thesis director)
- Azorsa, David (Committee member)
- Barrett, The Honors College (Contributor)
Topical Subject
Resource Type
Extent
17 pages
Language
Copyright Statement
In Copyright
Primary Member of
Series
Academic Year 2017-2018
Handle
https://hdl.handle.net/2286/R.I.45926
Level of coding
minimal
Cataloging Standards
System Created
- 2017-11-30 04:17:40
System Modified
- 2021-08-11 04:09:57
- 2 years 8 months ago
Additional Formats