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Title
  • Cancer as a Dynamical Phase Transition
Description

This paper discusses the properties of cancer cells from a new perspective based on an analogy with phase transitions in physical systems. Similarities in terms of instabilities and attractor states are outlined and differences discussed. While physical phase transitions typically…

This paper discusses the properties of cancer cells from a new perspective based on an analogy with phase transitions in physical systems. Similarities in terms of instabilities and attractor states are outlined and differences discussed. While physical phase transitions typically occur at or near thermodynamic equilibrium, a normal-to-cancer (NTC) transition is a dynamical non-equilibrium phenomenon, which depends on both metabolic energy supply and local physiological conditions. A number of implications for preventative and therapeutic strategies are outlined.

Contributors
Date Created
2011-08-25
Resource Type
  • Text
    • Collections this item is in
    ASU Regents' Professors Open Access Works
    Identifier
    • Digital object identifier: 10.1186/1742-4682-8-30
    • ISSN (International Standard Serial Number)
      1742-4682
    Note
    • The electronic version of this article is the complete one and can be found online at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177875/

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    This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.

    Davies, P. C., Demetrius, L., & Tuszynski, J. A. (2011). Cancer as a dynamical phase transition (30th ed., Vol. 8). THEORETICAL BIOLOGY AND MEDICAL MODELLING. doi:10.1186/1742-4682-8-30

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