Background: Concerns about the safety of paralytics such as succinylcholine to facilitate endotracheal intubation limit their use in prehospital and emergency department settings. The ability to rapidly reverse paralysis and restore respiratory drive would increase the safety margin of an agent, thus permitting the pursuit of alternative intubation strategies.
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- Geyer, Brian C. (Author)
- Larrimore, Katherine (Author)
- Kilbourne, Jacquelyn (Author)
- Kannan, Latha (Author)
- Mor, Tsafrir (Author)
- College of Liberal Arts and Sciences (Contributor)
- Digital object identifier: 10.1371/journal.pone.0059159
- Identifier TypeInternational standard serial numberIdentifier Value1932-6203
- This article also appears as published at http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0059159, opens in a new window
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Geyer BC, Larrimore KE, Kilbourne J, Kannan L, Mor TS (2013) Reversal of Succinylcholine Induced Apnea with an Organophosphate Scavenging Recombinant Butyrylcholinesterase. PLoS ONE 8(3): e59159. doi:10.1371/journal.pone.0059159