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Telomerase RNA (TER) is an essential component of the telomerase ribonucleoprotein complex. The mechanism for TER 3′-end processing is highly divergent among different organisms. Here we report a unique spliceosome-mediated

Telomerase RNA (TER) is an essential component of the telomerase ribonucleoprotein complex. The mechanism for TER 3′-end processing is highly divergent among different organisms. Here we report a unique spliceosome-mediated TER 3′-end cleavage mechanism in Neurospora crassa that is distinct from that found specifically in the fission yeast Schizosaccharomyces pombe. While the S. pombe TER intron contains the canonical 5′-splice site GUAUGU, the N.

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Date Created
  • 2015-01-01
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  • Text
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    Identifier
    • Digital object identifier: 10.1038/ncomms7105
    • Identifier Type
      International standard serial number
      Identifier Value
      0032-0633
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    Qi, Xiaodong, Rand, Dustin P., Podlevsky, Joshua D., Li, Yang, Mosig, Axel, Stadler, Peter F., & Chen, Julian J. -L. (2015). Prevalent and distinct spliceosomal 3 '-end processing mechanisms for fungal telomerase RNA. Nature Communications, 6: 6105. http://dx.doi.org/10.1038/ncomms7105

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