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Core-shell microgels containing sensors/dyes in a matrix were fabricated by two-stage free radical precipitation polymerization method for ratiometric sensing/imaging. The microgels composing of poly(N-isopropylacrylamide) (PNIPAm) shell exhibits a low critical

Core-shell microgels containing sensors/dyes in a matrix were fabricated by two-stage free radical precipitation polymerization method for ratiometric sensing/imaging. The microgels composing of poly(N-isopropylacrylamide) (PNIPAm) shell exhibits a low critical solution temperature (LCST), underwent an entropically driven transition from a swollen state to a deswollen state, which exhibit a hydrodynamic radius of ∼450 nm at 25°C (in vitro) and ∼190 nm at 37°C (in vivo).

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    Date Created
    • 2014-02-04
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0088185
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    Zhou, X., Su, F., Tian, Y., & Meldrum, D. R. (2014). Dually Fluorescent Core-Shell Microgels for Ratiometric Imaging in Live Antigen-Presenting Cells. PLoS ONE, 9(2). doi:10.1371/journal.pone.0088185

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