Description

Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells. MYXV is able to efficiently block all

Myxoma virus (MYXV) is Leporipoxvirus that possesses a specific rabbit‐restricted host tropism but exhibits a much broader cellular host range in cultured cells. MYXV is able to efficiently block all aspects of the type I interferon (IFN)‐induced antiviral state in rabbit cells, partially in human cells and very poorly in mouse cells. The mechanism(s) of this species‐specific inhibition of type I IFN‐induced antiviral state is not well understood.

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    Date Created
    • 2017-02-02
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.3390/v9020027
    • Identifier Type
      International standard serial number
      Identifier Value
      1999-4915

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    Rahman, M. M., & McFadden, G. (2017). Myxoma Virus dsRNA Binding Protein M029 Inhibits the Type I IFN‐Induced Antiviral State in a Highly Species‐Specific Fashion. Viruses, 9(2), 27. doi:10.3390/v9020027

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