Structural studies on living cells by conventional methods are limited to low resolution because radiation damage kills cells long before the necessary dose for high resolution can be delivered. X-ray free-electron lasers circumvent this problem by outrunning key damage processes with an ultra-short and extremely bright coherent X-ray pulse. Diffraction-before-destruction experiments provide high-resolution data from cells that are alive when the femtosecond X-ray pulse traverses the sample.
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- van der Schot, Gijs (Author)
- Svenda, Martin (Author)
- Maia, Filipe R. N. C. (Author)
- Hantke, Max F. (Author)
- DePonte, Daniel P. (Author)
- Seibert, M. Marvin (Author)
- Aquila, Andrew (Author)
- Schulz, Joachim (Author)
- Kirian, Richard (Contributor)
- Liang, Mengning (Author)
- Stellato, Francesco (Author)
- Bari, Sadia (Author)
- Iwan, Bianca (Author)
- Andreasson, Jakob (Author)
- Timneanu, Nicusor (Author)
- Bielecki, Johan (Author)
- Westphal, Daniel (Author)
- Nunes de Almeida, Francisca (Author)
- Odic, Dusko (Author)
- Hasse, Dirk (Author)
- Carlsson, Gunilla H. (Author)
- Larsson, Daniel S. D. (Author)
- Barty, Anton (Author)
- Martin, Andrew V. (Author)
- Schorb, Sebastian (Author)
- Bostedt, Christoph (Author)
- Bozek, John D. (Author)
- Carron, Sebastian (Author)
- Ferguson, Ken (Author)
- Rolles, Daniel (Author)
- Rudenko, Artem (Author)
- Epp, Sascha W. (Author)
- Foucar, Lutz (Author)
- Rudek, Benedikt (Author)
- Erk, Benjamin (Author)
- Hartmann, Robert (Author)
- Kimmel, Nils (Author)
- Holl, Peter (Author)
- Englert, Lars (Author)
- Loh, N. Duane (Author)
- Chapman, Henry N. (Author)
- Andersson, Inger (Author)
- Hajdu, Janos (Author)
- Ekeberg, Tomas (Author)
- College of Liberal Arts and Sciences (Contributor)
- 2016-08-01
- Digital object identifier: 10.1038/sdata.2016.58
- Identifier TypeInternational standard serial numberIdentifier Value2052-4463
- The final version of this article, as published in Scientific Data, can be viewed online at: https://www.nature.com/articles/sdata201658, opens in a new window
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Schot, G. V., Svenda, M., Maia, F. R., Hantke, M. F., Deponte, D. P., Seibert, M. M., . . . Ekeberg, T. (2016). Open data set of live cyanobacterial cells imaged using an X-ray laser. Scientific Data, 3, 160058. doi:10.1038/sdata.2016.58