Description

During X-ray exposure of a molecular solution, photons scattered from the same molecule are correlated. If molecular motion is insignificant during exposure, then differences in momentum transfer between correlated photons

During X-ray exposure of a molecular solution, photons scattered from the same molecule are correlated. If molecular motion is insignificant during exposure, then differences in momentum transfer between correlated photons are direct measurements of the molecular structure. In conventional small- and wide-angle solution scattering, photon correlations are ignored. This report presents advances in a new biomolecular structural analysis technique, correlated X-ray scattering (CXS), which uses angular intensity correlations to recover hidden structural details from molecules in solution.

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    Date Created
    • 2016-10-26
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1107/S2052252516013956
    • Identifier Type
      International standard serial number
      Identifier Value
      2052-2525

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    Mendez, D., Watkins, H., Qiao, S., Raines, K. S., Lane, T. J., Schenk, G., . . . Doniach, S. (2016). Angular correlations of photons from solution diffraction at a free-electron laser encode molecular structure. IUCrJ, 3(6), 420-429. doi:10.1107/s2052252516013956

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