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The most common evolutionary events at the molecular level are single-base substitutions, as well as insertions and deletions (indels) of short DNA segments. A large body of research has been

The most common evolutionary events at the molecular level are single-base substitutions, as well as insertions and deletions (indels) of short DNA segments. A large body of research has been devoted to develop probabilistic substitution models and to infer their parameters using likelihood and Bayesian approaches. In contrast, relatively little has been done to model indel dynamics, probably due to the difficulty in writing explicit likelihood functions.

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    Date Created
    • 2017-05-01
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  • Text
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    Identifier
    • Digital object identifier: 10.1093/gbe/evx084
    • Identifier Type
      International standard serial number
      Identifier Value
      1759-6653
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    Karin, E. L., Shkedy, D., Ashkenazy, H., Cartwright, R. A., & Pupko, T. (2017). Inferring Rates and Length-Distributions of Indels Using Approximate Bayesian Computation. Genome Biology and Evolution, 9(5), 1280-1294. doi:10.1093/gbe/evx084

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