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Salmonella enterica serovar Typhimurium genome encodes 13 fimbrial operons. Most of the fimbriae encoded by these operons are not produced under laboratory conditions but are likely to be synthesized in

Salmonella enterica serovar Typhimurium genome encodes 13 fimbrial operons. Most of the fimbriae encoded by these operons are not produced under laboratory conditions but are likely to be synthesized in vivo. We used an in vivo expression technology (IVET) strategy to identify four fimbrial operons, agf, saf, sti, and stc that are expressed in the spleen. When any three of these operons were deleted, the strain retained wild-type virulence.

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    Date Created
    • 2017-08-22
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    Identifier
    • Digital object identifier: 10.1128/mBio.01189-17
    • Identifier Type
      International standard serial number
      Identifier Value
      2150-7511
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    Łaniewski, P., Baek, C., Roland, K. L., & Curtiss, R. (2017). Analysis of Spleen-Induced Fimbria Production in Recombinant Attenuated Salmonella enterica Serovar Typhimurium Vaccine Strains. MBio, 8(4). doi:10.1128/mbio.01189-17

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