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mRNA expression dynamics promote and maintain the identity of somatic tissues in living organisms; however, their impact in post-transcriptional gene regulation in these processes is not fully understood. Here, we

mRNA expression dynamics promote and maintain the identity of somatic tissues in living organisms; however, their impact in post-transcriptional gene regulation in these processes is not fully understood. Here, we applied the PAT-Seq approach to systematically isolate, sequence, and map tissue-specific mRNA from five highly studied Caenorhabditis elegans somatic tissues: GABAergic and NMDA neurons, arcade and intestinal valve cells, seam cells, and hypodermal tissues, and studied their mRNA expression dynamics.

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    Date Created
    • 2017-03-27
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1534/genetics.116.196774
    • Identifier Type
      International standard serial number
      Identifier Value
      0016-6731
    • Identifier Type
      International standard serial number
      Identifier Value
      1943-2631
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    Blazie, S. M., Geissel, H. C., Wilky, H., Joshi, R., Newbern, J., & Mangone, M. (2017). Alternative Polyadenylation Directs Tissue-Specific miRNA Targeting in Caenorhabditis elegans Somatic Tissues. Genetics, 206(2), 757-774. doi:10.1534/genetics.116.196774

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