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Low fluid shear force, including that encountered in microgravity models, induces bacterial responses, but the range of bacteria capable of responding to this signal remains poorly characterized. We systematically analyzed

Low fluid shear force, including that encountered in microgravity models, induces bacterial responses, but the range of bacteria capable of responding to this signal remains poorly characterized. We systematically analyzed a range of Gram negative Enterobacteriaceae for conservation of the low-shear modeled microgravity (LSMMG) response using phenotypic assays, qPCR, and targeted mutations. Our results indicate LSMMG response conservation across Enterobacteriacae with potential variance in up- or down-regulation of a given response depending on genus.

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    Date Created
    • 2014
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    Identifier
    • Digital object identifier: 10.2174/1874285801408010051
    • Identifier Type
      International standard serial number
      Identifier Value
      1874-2858
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    Soni, A., O’Sullivan, L., Quick, L. N., Ott, C. M., Nickerson, C. A., & Wilson, J. W. (2014). Conservation of the Low-shear Modeled Microgravity Response in Enterobacteriaceae and Analysis of the trp Genes in this Response. The Open Microbiology Journal, 8(1), 51-58. doi:10.2174/1874285801408010051

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